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This page was generated on 2024-03-28 11:37:08 -0400 (Thu, 28 Mar 2024).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo1Linux (Ubuntu 22.04.3 LTS)x86_64R Under development (unstable) (2024-03-18 r86148) -- "Unsuffered Consequences" 4708
palomino3Windows Server 2022 Datacenterx64R Under development (unstable) (2024-03-16 r86144 ucrt) -- "Unsuffered Consequences" 4446
lconwaymacOS 12.7.1 Montereyx86_64R Under development (unstable) (2024-03-18 r86148) -- "Unsuffered Consequences" 4471
kunpeng2Linux (openEuler 22.03 LTS-SP1)aarch64R Under development (unstable) (2024-03-19 r86153) -- "Unsuffered Consequences" 4426
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 2026/2270HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
splatter 1.27.1  (landing page)
Luke Zappia
Snapshot Date: 2024-03-27 14:00:18 -0400 (Wed, 27 Mar 2024)
git_url: https://git.bioconductor.org/packages/splatter
git_branch: devel
git_last_commit: ea842a2
git_last_commit_date: 2024-03-26 16:18:58 -0400 (Tue, 26 Mar 2024)
nebbiolo1Linux (Ubuntu 22.04.3 LTS) / x86_64  OK    OK    ERROR  
palomino3Windows Server 2022 Datacenter / x64  OK    OK    WARNINGS    OK  YES
lconwaymacOS 12.7.1 Monterey / x86_64  OK    OK    ERROR    OK  
kunpeng2Linux (openEuler 22.03 LTS-SP1) / aarch64  OK    OK    ERROR  

CHECK results for splatter on nebbiolo1


To the developers/maintainers of the splatter package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/splatter.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: splatter
Version: 1.27.1
Command: /home/biocbuild/bbs-3.19-bioc/R/bin/R CMD check --install=check:splatter.install-out.txt --library=/home/biocbuild/bbs-3.19-bioc/R/site-library --timings splatter_1.27.1.tar.gz
StartedAt: 2024-03-28 03:01:13 -0400 (Thu, 28 Mar 2024)
EndedAt: 2024-03-28 03:09:51 -0400 (Thu, 28 Mar 2024)
EllapsedTime: 518.0 seconds
RetCode: 1
Status:   ERROR  
CheckDir: splatter.Rcheck
Warnings: NA

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/bbs-3.19-bioc/R/bin/R CMD check --install=check:splatter.install-out.txt --library=/home/biocbuild/bbs-3.19-bioc/R/site-library --timings splatter_1.27.1.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/home/biocbuild/bbs-3.19-bioc/meat/splatter.Rcheck’
* using R Under development (unstable) (2024-03-18 r86148)
* using platform: x86_64-pc-linux-gnu
* R was compiled by
    gcc (Ubuntu 11.4.0-1ubuntu1~22.04) 11.4.0
    GNU Fortran (Ubuntu 11.4.0-1ubuntu1~22.04) 11.4.0
* running under: Ubuntu 22.04.4 LTS
* using session charset: UTF-8
* checking for file ‘splatter/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘splatter’ version ‘1.27.1’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘splatter’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking loading without being on the library search path ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... WARNING
'library' or 'require' calls not declared from:
  ‘GenomicFeatures’ ‘TxDb.Hsapiens.UCSC.hg19.knownGene’
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                 user system elapsed
scDDEstimate   28.987  0.440  29.427
BASiCSSimulate  5.208  0.268   5.477
mockBulkeQTL    4.928  0.240   5.169
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘spelling.R’
  Running ‘testthat.R’
 ERROR
Running the tests in ‘tests/testthat.R’ failed.
Last 13 lines of output:
  77: test_code(test = NULL, code = exprs, env = env, default_reporter = StopReporter$new())
  78: source_file(path, env = env(env), desc = desc, error_call = error_call)
  79: FUN(X[[i]], ...)
  80: lapply(test_paths, test_one_file, env = env, desc = desc, error_call = error_call)
  81: doTryCatch(return(expr), name, parentenv, handler)
  82: tryCatchOne(expr, names, parentenv, handlers[[1L]])
  83: tryCatchList(expr, classes, parentenv, handlers)
  84: tryCatch(code, testthat_abort_reporter = function(cnd) {    cat(conditionMessage(cnd), "\n")    NULL})
  85: with_reporter(reporters$multi, lapply(test_paths, test_one_file,     env = env, desc = desc, error_call = error_call))
  86: test_files_serial(test_dir = test_dir, test_package = test_package,     test_paths = test_paths, load_helpers = load_helpers, reporter = reporter,     env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning,     desc = desc, load_package = load_package, error_call = error_call)
  87: test_files(test_dir = path, test_paths = test_paths, test_package = package,     reporter = reporter, load_helpers = load_helpers, env = env,     stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning,     load_package = load_package, parallel = parallel)
  88: test_dir("testthat", package = package, reporter = reporter,     ..., load_package = "installed")
  89: test_check("splatter")
  An irrecoverable exception occurred. R is aborting now ...
  Segmentation fault (core dumped)
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking re-building of vignette outputs ... OK
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 1 WARNING
See
  ‘/home/biocbuild/bbs-3.19-bioc/meat/splatter.Rcheck/00check.log’
for details.


Installation output

splatter.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/bbs-3.19-bioc/R/bin/R CMD INSTALL splatter
###
##############################################################################
##############################################################################


* installing to library ‘/home/biocbuild/bbs-3.19-bioc/R/site-library’
* installing *source* package ‘splatter’ ...
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (splatter)

Tests output

splatter.Rcheck/tests/spelling.Rout


R Under development (unstable) (2024-03-18 r86148) -- "Unsuffered Consequences"
Copyright (C) 2024 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> if (requireNamespace("spelling", quietly = TRUE)) {
+     spelling::spell_check_test(
+         vignettes = TRUE, error = FALSE,
+         skip_on_cran = TRUE
+     )
+ }
NULL
> 
> proc.time()
   user  system elapsed 
  0.158   0.039   0.184 

splatter.Rcheck/tests/testthat.Rout.fail


R Under development (unstable) (2024-03-18 r86148) -- "Unsuffered Consequences"
Copyright (C) 2024 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> # setting R_TESTS to empty string because of
> # https://github.com/hadley/testthat/issues/144
> # revert this when that issue in R is fixed.
> Sys.setenv("R_TESTS" = "")
> 
> library(testthat)
> library(splatter)
Loading required package: SingleCellExperiment
Loading required package: SummarizedExperiment
Loading required package: MatrixGenerics
Loading required package: matrixStats

Attaching package: 'MatrixGenerics'

The following objects are masked from 'package:matrixStats':

    colAlls, colAnyNAs, colAnys, colAvgsPerRowSet, colCollapse,
    colCounts, colCummaxs, colCummins, colCumprods, colCumsums,
    colDiffs, colIQRDiffs, colIQRs, colLogSumExps, colMadDiffs,
    colMads, colMaxs, colMeans2, colMedians, colMins, colOrderStats,
    colProds, colQuantiles, colRanges, colRanks, colSdDiffs, colSds,
    colSums2, colTabulates, colVarDiffs, colVars, colWeightedMads,
    colWeightedMeans, colWeightedMedians, colWeightedSds,
    colWeightedVars, rowAlls, rowAnyNAs, rowAnys, rowAvgsPerColSet,
    rowCollapse, rowCounts, rowCummaxs, rowCummins, rowCumprods,
    rowCumsums, rowDiffs, rowIQRDiffs, rowIQRs, rowLogSumExps,
    rowMadDiffs, rowMads, rowMaxs, rowMeans2, rowMedians, rowMins,
    rowOrderStats, rowProds, rowQuantiles, rowRanges, rowRanks,
    rowSdDiffs, rowSds, rowSums2, rowTabulates, rowVarDiffs, rowVars,
    rowWeightedMads, rowWeightedMeans, rowWeightedMedians,
    rowWeightedSds, rowWeightedVars

Loading required package: GenomicRanges
Loading required package: stats4
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, table, tapply,
    union, unique, unsplit, which.max, which.min

Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following object is masked from 'package:utils':

    findMatches

The following objects are masked from 'package:base':

    I, expand.grid, unname

Loading required package: IRanges
Loading required package: GenomeInfoDb
Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.


Attaching package: 'Biobase'

The following object is masked from 'package:MatrixGenerics':

    rowMedians

The following objects are masked from 'package:matrixStats':

    anyMissing, rowMedians

> 
> test_check("splatter")

 *** caught segfault ***
address (nil), cause 'unknown'

Traceback:
 1: .Call(merPredDCreate, as(X, "matrix"), Lambdat, LamtUt, Lind,     RZX, Ut, Utr, V, VtV, Vtr, Xwts, Zt, beta0, delb, delu, theta,     u0)
 2: initializePtr()
 3: .Object$initialize(...)
 4: initialize(value, ...)
 5: initialize(value, ...)
 6: methods::new(def, ...)
 7: (new("refMethodDef", .Data = function (...) {    methods::new(def, ...)}, mayCall = c("methods", "new"), name = "new", refClassName = "refGeneratorSlot",     superClassMethod = ""))(Zt = new("dgCMatrix", i = c(0L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 0L, 1L, 1L, 0L, 1L, 1L, 1L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 1L, 1L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 0L, 0L, 1L, 1L, 1L, 0L, 0L, 1L, 1L, 1L, 0L, 0L, 0L, 0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 1L, 0L, 1L, 1L, 0L, 1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 1L, 0L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L, 0L, 0L, 1L, 1L, 1L, 0L, 1L, 0L, 1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 1L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 1L, 0L, 1L, 1L, 1L, 1L), p = 0:200, Dim = c(2L, 200L), Dimnames = list(    c("1", "2"), c("1", "2", "3", "4", "5", "6", "7", "8", "9",     "10", "11", "12", "13", "14", "15", "16", "17", "18", "19",     "20", "21", "22", "23", "24", "25", "26", "27", "28", "29",     "30", "31", "32", "33", "34", "35", "36", "37", "38", "39",     "40", "41", "42", "43", "44", "45", "46", "47", "48", "49",     "50", "51", "52", "53", "54", "55", "56", "57", "58", "59",     "60", "61", "62", "63", "64", "65", "66", "67", "68", "69",     "70", "71", "72", "73", "74", "75", "76", "77", "78", "79",     "80", "81", "82", "83", "84", "85", "86", "87", "88", "89",     "90", "91", "92", "93", "94", "95", "96", "97", "98", "99",     "100", "101", "102", "103", "104", "105", "106", "107", "108",     "109", "110", "111", "112", "113", "114", "115", "116", "117",     "118", "119", "120", "121", "122", "123", "124", "125", "126",     "127", "128", "129", "130", "131", "132", "133", "134", "135",     "136", "137", "138", "139", "140", "141", "142", "143", "144",     "145", "146", "147", "148", "149", "150", "151", "152", "153",     "154", "155", "156", "157", "158", "159", "160", "161", "162",     "163", "164", "165", "166", "167", "168", "169", "170", "171",     "172", "173", "174", "175", "176", "177", "178", "179", "180",     "181", "182", "183", "184", "185", "186", "187", "188", "189",     "190", "191", "192", "193", "194", "195", "196", "197", "198",     "199", "200")), x = c(1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1),     factors = list()), theta = 1, Lambdat = new("dgCMatrix",     i = 0:1, p = 0:2, Dim = c(2L, 2L), Dimnames = list(NULL,         NULL), x = c(1, 1), factors = list()), Lind = c(1L, 1L), n = 200L, X = numeric(0))
 8: do.call(merPredD$new, c(reTrms[c("Zt", "theta", "Lambdat", "Lind")],     n = nrow(X), list(X = X)))
 9: (function (fr, X, reTrms, family, nAGQ = 1L, verbose = 0L, maxit = 100L,     control = glmerControl(), ...) {    stopifnot(length(nAGQ <- as.integer(nAGQ)) == 1L, 0L <= nAGQ,         nAGQ <= 25L)    verbose <- as.integer(verbose)    maxit <- as.integer(maxit)    rho <- list2env(list(verbose = verbose, maxit = maxit, tolPwrss = control$tolPwrss,         compDev = control$compDev), parent = parent.frame())    rho$pp <- do.call(merPredD$new, c(reTrms[c("Zt", "theta",         "Lambdat", "Lind")], n = nrow(X), list(X = X)))    rho$resp <- if (missing(fr))         mkRespMod(family = family, ...)    else mkRespMod(fr, family = family)    nAGQinit <- if (control$nAGQ0initStep)         0L    else 1L    if (length(y <- rho$resp$y) > 0) {        checkResponse(y, control$checkControl)        rho$verbose <- as.integer(verbose)        .Call(glmerLaplace, rho$pp$ptr(), rho$resp$ptr(), nAGQinit,             control$tolPwrss, maxit, verbose)        rho$lp0 <- rho$pp$linPred(1)        rho$pwrssUpdate <- glmerPwrssUpdate    }    rho$lower <- reTrms$lower    mkdevfun(rho, nAGQinit, maxit = maxit, verbose = verbose,         control = control)})(fr = list(Counts = c(2L, 38L, 7L, 121L, 22L, 6L, 4L, 64L, 2L, 150L, 202L, 23L, 4L, 14L, 121L, 13L, 8L, 8L, 242L, 0L, 0L, 49L, 31L, 109L, 13L, 4L, 0L, 111L, 77L, 3L, 47L, 24L, 20L, 9L, 18L, 411L, 1L, 66L, 22L, 7L, 47L, 0L, 341L, 17L, 27L, 0L, 3L, 0L, 91L, 26L, 24L, 0L, 25L, 2L, 24L, 56L, 160L, 75L, 28L, 21L, 53L, 23L, 0L, 128L, 23L, 25L, 86L, 1L, 254L, 390L, 27L, 107L, 576L, 211L, 9L, 29L, 44L, 2L, 33L, 42L, 42L, 43L, 82L, 2L, 222L, 86L, 34L, 0L, 0L, 2L, 41L, 8L, 70L, 153L, 13L, 3L, 5L, 2L, 50L, 0L, 0L, 135L, 125L, 28L, 53L, 93L, 32L, 4L, 119L, 24L, 2L, 9L, 196L, 19L, 28L, 2L, 5L, 266L, 350L, 355L, 54L, 47L, 7L, 0L, 0L, 175L, 104L, 233L, 0L, 135L, 35L, 4L, 2L, 0L, 14L, 0L, 26L, 55L, 267L, 8L, 5L, 0L, 120L, 27L, 269L, 3L, 6L, 1L, 4L, 0L, 12L, 1L, 8L, 14L, 34L, 17L, 222L, 83L, 249L, 160L, 3L, 10L, 24L, 25L, 20L, 154L, 128L, 9L, 15L, 40L, 2L, 55L, 0L, 15L, 59L, 2L, 312L, 17L, 168L, 293L, 13L, 20L, 13L, 74L, 52L, 111L, 11L, 25L, 3L, 0L, 172L, 91L, 10L, 125L, 50L, 105L, 129L, 4L, 5L, 1L), Plate = c(1, 1, 1, 1, 1, 2, 1, 2, 1, 1, 2, 1, 1, 1, 1, 2, 1, 2, 1, 2, 2, 1, 2, 2, 2, 1, 2, 1, 2, 2, 1, 1, 2, 2, 1, 1, 2, 2, 1, 2, 2, 1, 1, 2, 1, 2, 2, 1, 1, 1, 1, 2, 2, 2, 1, 1, 2, 2, 2, 1, 1, 1, 1, 2, 2, 1, 1, 2, 2, 1, 1, 1, 2, 1, 1, 1, 1, 2, 2, 1, 2, 2, 1, 2, 2, 1, 1, 1, 1, 1, 1, 2, 1, 2, 2, 1, 1, 2, 2, 1, 2, 1, 1, 2, 2, 2, 2, 1, 2, 1, 1, 2, 1, 1, 2, 1, 2, 2, 1, 2, 1, 1, 1, 1, 2, 1, 1, 1, 2, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 1, 2, 2, 2, 1, 1, 1, 1, 1, 1, 1, 2, 1, 1, 2, 1, 1, 2, 1, 1, 2, 2, 2, 2, 1, 1, 2, 2, 2, 1, 2, 1, 2, 1, 1, 1, 2, 1, 1, 1, 1, 1, 1, 2, 2, 1, 1, 1, 2, 1, 2, 2, 2, 1, 2, 2, 2, 2), `offset(log(sum.facs))` = c(0.099415038869768, -0.379828545048838, 0.0565696897829142, -0.258408386822744, -0.0877856880672727, -0.061543992625483, 0.046118508036817, 0.124271161877116, 0.185563023618431, 0.0863593950919948, -0.56345492759145, -0.189566668681887, 0.345767454613878, -0.0372016838241394, -0.831886866637659, -0.0440024012845792, 0.0613439280644819, 0.165855683642866, 0.507531750908371, -1.63388034585584, -0.0386339210428579, -0.178769808549106, -0.0425102686041306, -0.351441593254914, 0.14095725379126, -0.26034419645512, 0.00166255613855808, -0.415477390512743, 0.346928632583233, -0.0864072091674503, -0.315932159081673, -0.362353549353006, -1.03144216141072, -0.0133032735950596, -0.268983625968043, -0.298709345622086, -0.231983628441647, 0.0454259104208528, -0.0967765348845144, 0.187307121445735, 0.320792525358586, 0.264803079837192, 0.0844968886935661, 0.0831660920106556, 0.164077650428171, -0.183924667792603, -0.014594381370487, 0.675728251106668, -0.013946110473825, -0.431604456155111, 0.383035094710592, -0.017585303406751, 0.177330480039961, -0.406149859243613, -0.602820074084561, -0.363704526604013, -0.354627231387144, -0.778615690929021, -0.0249333214810372, 0.125879376223266, -0.146611868232665, 0.494738747027579, 0.264539745647939, -0.0138339579865562, -0.0604923897108628, 0.531143769641901, -0.593642871849057, -0.262127296526215, -0.300470213862321, -0.658375555914743, 0.174298844139928, 0.114146943666202, -0.0124292692295182, -0.281796727453792, 0.0500745786980265, 0.487278679759632, -0.414002615442896, 0.123918150393643, -1.67445131941827, -0.379312963276262, 0.338238089202279, -0.0280385241180911, 0.491652947938528, 0.166221014704874, 0.0684744686639439, -0.499231203535198, 0.544133310959025, 0.191440739948786, -0.207407409381184, 0.229531947788602, -0.0744338695765945, 0.26291083158208, -0.176558738508868, -0.0165011025009814, -0.241101747569872, -0.374537883964343, 0.217453927920594, 0.0916019299158345, -0.267169816259059, 0.28168700573108, 0.083552451542729, 0.177536610172399, 0.147078865094902, 0.18084870055571, 0.215486382213473, -0.0670453434445629, 0.0706094552105798, -0.169274626291377, -0.292817173334925, -0.0152435039760019, -0.24875605596651, -0.0460293642921873, -0.0553245236163159, 0.338374893785228, -0.27367726719201, -0.290627469059366, -0.20419510573265, 0.218431077035407, -0.31200368462525, -0.648966507946428, -0.313398141379113, -0.830242165624212, 0.225923023725423, 0.183029838140348, -0.447277964821486, -0.173375782776695, 0.00471047922889148, -0.321521187389957, 0.18196253465792, -0.0216396893215089, -0.351905863041009, -0.0192115633603184, 0.165829955476795, -0.173942913084997, -0.195331196655357, 0.176171914543302, -0.0795758985096257, 0.33155884934634, 0.19574447381189, 0.197774296858661, 0.0676302223084067, 0.407952554798438, 0.216850807866717, 0.00604410710748176, 0.803126522955307, 0.675728251106668, -0.372698050367551, 0.338630033620027, -0.216075753117768, 0.176081664524125, -0.253469961953984, -0.102201224725323, 0.0169984361044372, -0.0704423920086104, -0.0724707300008174, -0.121603175804744, -0.459532898869912, 0.139916591758436, -0.275667166793369, 0.1107731799318, -0.757129363510934, 0.0176135938565981, 0.1559824399534, 0.0636812033678214, -0.272654800281362, -0.156896086646592, -0.656250949898347, -0.145374157295841, 0.0926137350986882, 0.110450101702026, 0.391711886004828, -0.0611105358770773, -0.0499677364991217, -0.532172793155276, 0.058888807355348, 0.641706754959037, -0.238810405414909, -0.429164702074668, -0.468971467453558, 0.455665563044504, 0.234161398733825, 0.587380893468882, 0.394329769151368, -0.221856048734092, 0.129582289777065, -0.0867136784063051, 0.402820389425792, 0.160213846167719, -0.175785045410078, 0.0436768400925117, -0.407844509600082, 0.0988681398910556, -0.297252034675955, -0.0552115503889233, -0.00403808176848588, 0.278589302086595, -0.3961197682938, 0.157839055803157, -0.368190692687059, -0.169832650269634)), X = numeric(0), reTrms = list(    Zt = new("dgCMatrix", i = c(0L, 0L, 0L, 0L, 0L, 1L, 0L, 1L,     0L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 0L, 1L, 1L, 0L, 1L,     1L, 1L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 0L, 1L, 1L,     0L, 1L, 1L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 0L, 0L, 1L, 1L,     1L, 0L, 0L, 1L, 1L, 1L, 0L, 0L, 0L, 0L, 1L, 1L, 0L, 0L, 1L,     1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 1L, 0L, 1L, 1L, 0L,     1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 0L, 1L,     1L, 0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L, 0L, 1L, 0L, 0L, 1L, 0L,     0L, 1L, 0L, 1L, 1L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 0L, 0L, 0L,     1L, 0L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L,     1L, 1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 0L, 0L, 1L, 0L,     0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L, 0L, 0L, 1L, 1L, 1L, 0L, 1L,     0L, 1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 1L, 1L, 0L,     0L, 0L, 1L, 0L, 1L, 1L, 1L, 0L, 1L, 1L, 1L, 1L), p = 0:200,         Dim = c(2L, 200L), Dimnames = list(c("1", "2"), c("1",         "2", "3", "4", "5", "6", "7", "8", "9", "10", "11", "12",         "13", "14", "15", "16", "17", "18", "19", "20", "21",         "22", "23", "24", "25", "26", "27", "28", "29", "30",         "31", "32", "33", "34", "35", "36", "37", "38", "39",         "40", "41", "42", "43", "44", "45", "46", "47", "48",         "49", "50", "51", "52", "53", "54", "55", "56", "57",         "58", "59", "60", "61", "62", "63", "64", "65", "66",         "67", "68", "69", "70", "71", "72", "73", "74", "75",         "76", "77", "78", "79", "80", "81", "82", "83", "84",         "85", "86", "87", "88", "89", "90", "91", "92", "93",         "94", "95", "96", "97", "98", "99", "100", "101", "102",         "103", "104", "105", "106", "107", "108", "109", "110",         "111", "112", "113", "114", "115", "116", "117", "118",         "119", "120", "121", "122", "123", "124", "125", "126",         "127", "128", "129", "130", "131", "132", "133", "134",         "135", "136", "137", "138", "139", "140", "141", "142",         "143", "144", "145", "146", "147", "148", "149", "150",         "151", "152", "153", "154", "155", "156", "157", "158",         "159", "160", "161", "162", "163", "164", "165", "166",         "167", "168", "169", "170", "171", "172", "173", "174",         "175", "176", "177", "178", "179", "180", "181", "182",         "183", "184", "185", "186", "187", "188", "189", "190",         "191", "192", "193", "194", "195", "196", "197", "198",         "199", "200")), x = c(1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,         1, 1, 1, 1, 1, 1, 1, 1, 1), factors = list()), theta = 1,     Lind = c(1L, 1L), Gp = c(0L, 2L), lower = 0, Lambdat = new("dgCMatrix",         i = 0:1, p = 0:2, Dim = c(2L, 2L), Dimnames = list(NULL,             NULL), x = c(1, 1), factors = list()), flist = list(        Plate = c(1L, 1L, 1L, 1L, 1L, 2L, 1L, 2L, 1L, 1L, 2L,         1L, 1L, 1L, 1L, 2L, 1L, 2L, 1L, 2L, 2L, 1L, 2L, 2L, 2L,         1L, 2L, 1L, 2L, 2L, 1L, 1L, 2L, 2L, 1L, 1L, 2L, 2L, 1L,         2L, 2L, 1L, 1L, 2L, 1L, 2L, 2L, 1L, 1L, 1L, 1L, 2L, 2L,         2L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 2L, 2L, 1L, 1L,         2L, 2L, 1L, 1L, 1L, 2L, 1L, 1L, 1L, 1L, 2L, 2L, 1L, 2L,         2L, 1L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 1L, 2L, 2L,         1L, 1L, 2L, 2L, 1L, 2L, 1L, 1L, 2L, 2L, 2L, 2L, 1L, 2L,         1L, 1L, 2L, 1L, 1L, 2L, 1L, 2L, 2L, 1L, 2L, 1L, 1L, 1L,         1L, 2L, 1L, 1L, 1L, 2L, 1L, 2L, 1L, 1L, 1L, 1L, 1L, 1L,         1L, 1L, 1L, 1L, 2L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L,         1L, 1L, 2L, 1L, 1L, 2L, 1L, 1L, 2L, 1L, 1L, 2L, 2L, 2L,         2L, 1L, 1L, 2L, 2L, 2L, 1L, 2L, 1L, 2L, 1L, 1L, 1L, 2L,         1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 1L, 1L, 1L, 2L, 1L, 2L,         2L, 2L, 1L, 2L, 2L, 2L, 2L)), cnms = list(Plate = "(Intercept)"),     Ztlist = list(`1 | Plate` = new("dgCMatrix", i = c(0L, 0L,     0L, 0L, 0L, 1L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 0L, 0L, 1L, 0L,     1L, 0L, 1L, 1L, 0L, 1L, 1L, 1L, 0L, 1L, 0L, 1L, 1L, 0L, 0L,     1L, 1L, 0L, 0L, 1L, 1L, 0L, 1L, 1L, 0L, 0L, 1L, 0L, 1L, 1L,     0L, 0L, 0L, 0L, 1L, 1L, 1L, 0L, 0L, 1L, 1L, 1L, 0L, 0L, 0L,     0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L, 0L,     1L, 1L, 0L, 1L, 1L, 0L, 1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L, 1L,     0L, 1L, 1L, 0L, 0L, 1L, 1L, 0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L,     0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 0L, 1L, 1L, 0L, 1L, 0L, 0L,     0L, 0L, 1L, 0L, 0L, 0L, 1L, 0L, 1L, 0L, 0L, 0L, 0L, 0L, 0L,     0L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 1L, 0L, 0L, 0L, 0L, 0L, 0L,     0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 0L, 0L, 1L, 1L, 1L, 1L, 0L,     0L, 1L, 1L, 1L, 0L, 1L, 0L, 1L, 0L, 0L, 0L, 1L, 0L, 0L, 0L,     0L, 0L, 0L, 1L, 1L, 0L, 0L, 0L, 1L, 0L, 1L, 1L, 1L, 0L, 1L,     1L, 1L, 1L), p = 0:200, Dim = c(2L, 200L), Dimnames = list(        c("1", "2"), c("1", "2", "3", "4", "5", "6", "7", "8",         "9", "10", "11", "12", "13", "14", "15", "16", "17",         "18", "19", "20", "21", "22", "23", "24", "25", "26",         "27", "28", "29", "30", "31", "32", "33", "34", "35",         "36", "37", "38", "39", "40", "41", "42", "43", "44",         "45", "46", "47", "48", "49", "50", "51", "52", "53",         "54", "55", "56", "57", "58", "59", "60", "61", "62",         "63", "64", "65", "66", "67", "68", "69", "70", "71",         "72", "73", "74", "75", "76", "77", "78", "79", "80",         "81", "82", "83", "84", "85", "86", "87", "88", "89",         "90", "91", "92", "93", "94", "95", "96", "97", "98",         "99", "100", "101", "102", "103", "104", "105", "106",         "107", "108", "109", "110", "111", "112", "113", "114",         "115", "116", "117", "118", "119", "120", "121", "122",         "123", "124", "125", "126", "127", "128", "129", "130",         "131", "132", "133", "134", "135", "136", "137", "138",         "139", "140", "141", "142", "143", "144", "145", "146",         "147", "148", "149", "150", "151", "152", "153", "154",         "155", "156", "157", "158", "159", "160", "161", "162",         "163", "164", "165", "166", "167", "168", "169", "170",         "171", "172", "173", "174", "175", "176", "177", "178",         "179", "180", "181", "182", "183", "184", "185", "186",         "187", "188", "189", "190", "191", "192", "193", "194",         "195", "196", "197", "198", "199", "200")), x = c(1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1,     1, 1, 1, 1, 1, 1, 1, 1, 1), factors = list())), nl = c(Plate = 2L)),     family = list(family = "Negative Binomial(0.4099)", link = "log",         linkfun = function (mu)         log(mu), linkinv = function (eta)         pmax(exp(eta), .Machine$double.eps), variance = function (mu)         mu + mu^2/.Theta, dev.resids = function (y, mu, wt)         2 * wt * (y * log(pmax(1, y)/mu) - (y + .Theta) * log((y +             .Theta)/(mu + .Theta))), aic = function (y, n, mu,             wt, dev)         {            term <- (y + .Theta) * log(mu + .Theta) - y * log(mu) +                 lgamma(y + 1) - .Theta * log(.Theta) + lgamma(.Theta) -                 lgamma(.Theta + y)            2 * sum(term * wt)        }, mu.eta = function (eta)         pmax(exp(eta), .Machine$double.eps), initialize = expression(            {                if (any(y < 0))                   stop("negative values not allowed for the negative binomial family")                n <- rep(1, nobs)                mustart <- y + (y == 0)/6            }), validmu = function (mu)         all(mu > 0), valideta = function (eta)         TRUE, simulate = function (object, nsim)         {            ftd <- fitted(object)            rnegbin(nsim * length(ftd), ftd, .Theta)        }), wmsgs = character(0), verbose = 0L, control = list(        optimizer = c("bobyqa", "Nelder_Mead"), restart_edge = FALSE,         boundary.tol = 1e-05, calc.derivs = TRUE, use.last.params = FALSE,         checkControl = list(check.nobs.vs.rankZ = "ignore", check.nobs.vs.nlev = "stop",             check.nlev.gtreq.5 = "ignore", check.nlev.gtr.1 = "stop",             check.nobs.vs.nRE = "stop", check.rankX = "message+drop.cols",             check.scaleX = "warning", check.formula.LHS = "stop",             check.response.not.const = "stop"), checkConv = list(            check.conv.grad = list(action = "warning", tol = 0.002,                 relTol = NULL), check.conv.singular = list(action = "message",                 tol = 1e-04), check.conv.hess = list(action = "warning",                 tol = 1e-06)), optCtrl = list(), tolPwrss = 1e-07,         compDev = TRUE, nAGQ0initStep = TRUE), nAGQ = 0L)
10: do.call(mkGlmerDevfun, c(glmod, list(verbose = verbose, control = control,     nAGQ = nAGQinit)))
11: lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),     data = data.frame(Counts = as.integer(counts[i, ]), Group = groups,         Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))
12: doTryCatch(return(expr), name, parentenv, handler)
13: tryCatchOne(expr, names, parentenv, handlers[[1L]])
14: tryCatchList(expr, classes, parentenv, handlers)
15: tryCatch({    out <- lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),         data = data.frame(Counts = as.integer(counts[i, ]), Group = groups,             Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))    output <- unlist(lme4::VarCorr(out))    return(output)}, error = function(err) {    output <- NA_real_    return(output)})
16: FUN(...)
17: withCallingHandlers({    ERROR_CALL_DEPTH <<- (function() sys.nframe() - 1L)()    FUN(...)}, error = function(e) {    annotated_condition <- handle_error(e)    stop(annotated_condition)}, warning = handle_warning)
18: doTryCatch(return(expr), name, parentenv, handler)
19: tryCatchOne(expr, names, parentenv, handlers[[1L]])
20: tryCatchList(expr, classes, parentenv, handlers)
21: tryCatch({    withCallingHandlers({        ERROR_CALL_DEPTH <<- (function() sys.nframe() - 1L)()        FUN(...)    }, error = function(e) {        annotated_condition <- handle_error(e)        stop(annotated_condition)    }, warning = handle_warning)}, error = identity)
22: FUN(X[[i]], ...)
23: (function (X, FUN, ...) {    FUN <- match.fun(FUN)    if (!is.vector(X) || is.object(X))         X <- as.list(X)    .Internal(lapply(X, FUN))})(X = 1:100, FUN = function (...) {    if (!identical(timeout, WORKER_TIMEOUT)) {        setTimeLimit(timeout, timeout, TRUE)        on.exit(setTimeLimit(Inf, Inf, FALSE))    }    if (!is.null(globalOptions))         base::options(globalOptions)    if (stop.on.error && ERROR_OCCURRED) {        UNEVALUATED    }    else {        .rng_reset_generator("L'Ecuyer-CMRG", SEED)        output <- tryCatch({            withCallingHandlers({                ERROR_CALL_DEPTH <<- (function() sys.nframe() -                   1L)()                FUN(...)            }, error = function(e) {                annotated_condition <- handle_error(e)                stop(annotated_condition)            }, warning = handle_warning)        }, error = identity)        if (force.GC)             gc(verbose = FALSE, full = FALSE)        SEED <<- .rng_next_substream(SEED)        output    }})
24: do.call(lapply, args)
25: BiocParallel:::.workerLapply_impl(...)
26: (function (...) BiocParallel:::.workerLapply_impl(...))(X = 1:100, FUN = function (i) {    if (progress) {        pb$tick()    }    tryCatch({        out <- lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),             data = data.frame(Counts = as.integer(counts[i, ]),                 Group = groups, Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))        output <- unlist(lme4::VarCorr(out))        return(output)    }, error = function(err) {        output <- NA_real_        return(output)    })}, ARGS = list(), OPTIONS = list(log = FALSE, threshold = "INFO",     stop.on.error = TRUE, as.error = TRUE, timeout = NA_integer_,     force.GC = FALSE, globalOptions = NULL), BPRNGSEED = c(10407L, 5612845L, -2000336471L, -920356484L, -1763755710L, -845292742L, -674606688L), GLOBALS = list(), PACKAGES = character(0))
27: do.call(msg$data$fun, msg$data$args)
28: doTryCatch(return(expr), name, parentenv, handler)
29: tryCatchOne(expr, names, parentenv, handlers[[1L]])
30: tryCatchList(expr, classes, parentenv, handlers)
31: tryCatch({    do.call(msg$data$fun, msg$data$args)}, error = function(e) {    list(.error_worker_comm(e, "worker evaluation failed"))})
32: .bpworker_EXEC(msg, bplog(backend$BPPARAM))
33: .recv_any(manager$backend)
34: .recv_any(manager$backend)
35: .manager_recv(manager)
36: .manager_recv(manager)
37: .collect_result(manager, reducer, progress, BPPARAM)
38: .bploop_impl(ITER = ITER, FUN = FUN, ARGS = ARGS, BPPARAM = BPPARAM,     BPOPTIONS = BPOPTIONS, BPREDO = BPREDO, reducer = reducer,     progress.length = length(redo_index))
39: bploop.lapply(manager, BPPARAM = BPPARAM, BPOPTIONS = BPOPTIONS,     ...)
40: bploop(manager, BPPARAM = BPPARAM, BPOPTIONS = BPOPTIONS, ...)
41: .bpinit(manager = manager, X = X, FUN = FUN, ARGS = ARGS, BPPARAM = BPPARAM,     BPOPTIONS = BPOPTIONS, BPREDO = BPREDO)
42: bplapply(seq_len(nrow(dge)), function(i) {    if (progress) {        pb$tick()    }    tryCatch({        out <- lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),             data = data.frame(Counts = as.integer(counts[i, ]),                 Group = groups, Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))        output <- unlist(lme4::VarCorr(out))        return(output)    }, error = function(err) {        output <- NA_real_        return(output)    })}, BPPARAM = BPPARAM)
43: bplapply(seq_len(nrow(dge)), function(i) {    if (progress) {        pb$tick()    }    tryCatch({        out <- lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),             data = data.frame(Counts = as.integer(counts[i, ]),                 Group = groups, Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))        output <- unlist(lme4::VarCorr(out))        return(output)    }, error = function(err) {        output <- NA_real_        return(output)    })}, BPPARAM = BPPARAM)
44: withCallingHandlers(expr, warning = function(w) if (inherits(w,     classes)) tryInvokeRestart("muffleWarning"))
45: suppressWarnings(collected <- bplapply(seq_len(nrow(dge)), function(i) {    if (progress) {        pb$tick()    }    tryCatch({        out <- lme4::glmer(Counts ~ 0 + (1 | Plate) + offset(log(sum.facs)),             data = data.frame(Counts = as.integer(counts[i, ]),                 Group = groups, Plate = plates), family = lme4::negative.binomial(1/dge$tagwise[i]))        output <- unlist(lme4::VarCorr(out))        return(output)    }, error = function(err) {        output <- NA_real_        return(output)    })}, BPPARAM = BPPARAM))
46: lun2Estimate.matrix(counts, plates, params, min.size = min.size,     verbose = verbose, BPPARAM = BPPARAM)
47: lun2Estimate(counts, plates, params, min.size = min.size, verbose = verbose,     BPPARAM = BPPARAM)
48: lun2Estimate.SingleCellExperiment(sce, plates, min.size = 20)
49: lun2Estimate(sce, plates, min.size = 20)
50: eval_bare(quo_get_expr(.quo), quo_get_env(.quo))
51: withCallingHandlers(code, warning = function(condition) {    if (ignore_deprecation && is_deprecation(condition)) {        return()    }    out$push(condition)    maybe_restart("muffleWarning")})
52: .capture(act$val <- eval_bare(quo_get_expr(.quo), quo_get_env(.quo)),     ...)
53: quasi_capture(enquo(object), label, capture_warnings, ignore_deprecation = identical(regexp,     NA))
54: expect_warning(lun2Estimate(sce, plates, min.size = 20), "more singular values")
55: eval(code, test_env)
56: eval(code, test_env)
57: withCallingHandlers({    eval(code, test_env)    if (!handled && !is.null(test)) {        skip_empty()    }}, expectation = handle_expectation, skip = handle_skip, warning = handle_warning,     message = handle_message, error = handle_error)
58: doTryCatch(return(expr), name, parentenv, handler)
59: tryCatchOne(expr, names, parentenv, handlers[[1L]])
60: tryCatchList(expr, names[-nh], parentenv, handlers[-nh])
61: doTryCatch(return(expr), name, parentenv, handler)
62: tryCatchOne(tryCatchList(expr, names[-nh], parentenv, handlers[-nh]),     names[nh], parentenv, handlers[[nh]])
63: tryCatchList(expr, classes, parentenv, handlers)
64: tryCatch(withCallingHandlers({    eval(code, test_env)    if (!handled && !is.null(test)) {        skip_empty()    }}, expectation = handle_expectation, skip = handle_skip, warning = handle_warning,     message = handle_message, error = handle_error), error = handle_fatal,     skip = function(e) {    })
65: test_code(desc, code, env = parent.frame(), default_reporter = local_interactive_reporter())
66: test_that("lun2Estimate works", {    plates <- as.numeric(factor(colData(sce)$Mutation_Status))    params <- expect_warning(lun2Estimate(sce, plates, min.size = 20),         "more singular values")    expect_true(validObject(params))})
67: eval(code, test_env)
68: eval(code, test_env)
69: withCallingHandlers({    eval(code, test_env)    if (!handled && !is.null(test)) {        skip_empty()    }}, expectation = handle_expectation, skip = handle_skip, warning = handle_warning,     message = handle_message, error = handle_error)
70: doTryCatch(return(expr), name, parentenv, handler)
71: tryCatchOne(expr, names, parentenv, handlers[[1L]])
72: tryCatchList(expr, names[-nh], parentenv, handlers[-nh])
73: doTryCatch(return(expr), name, parentenv, handler)
74: tryCatchOne(tryCatchList(expr, names[-nh], parentenv, handlers[-nh]),     names[nh], parentenv, handlers[[nh]])
75: tryCatchList(expr, classes, parentenv, handlers)
76: tryCatch(withCallingHandlers({    eval(code, test_env)    if (!handled && !is.null(test)) {        skip_empty()    }}, expectation = handle_expectation, skip = handle_skip, warning = handle_warning,     message = handle_message, error = handle_error), error = handle_fatal,     skip = function(e) {    })
77: test_code(test = NULL, code = exprs, env = env, default_reporter = StopReporter$new())
78: source_file(path, env = env(env), desc = desc, error_call = error_call)
79: FUN(X[[i]], ...)
80: lapply(test_paths, test_one_file, env = env, desc = desc, error_call = error_call)
81: doTryCatch(return(expr), name, parentenv, handler)
82: tryCatchOne(expr, names, parentenv, handlers[[1L]])
83: tryCatchList(expr, classes, parentenv, handlers)
84: tryCatch(code, testthat_abort_reporter = function(cnd) {    cat(conditionMessage(cnd), "\n")    NULL})
85: with_reporter(reporters$multi, lapply(test_paths, test_one_file,     env = env, desc = desc, error_call = error_call))
86: test_files_serial(test_dir = test_dir, test_package = test_package,     test_paths = test_paths, load_helpers = load_helpers, reporter = reporter,     env = env, stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning,     desc = desc, load_package = load_package, error_call = error_call)
87: test_files(test_dir = path, test_paths = test_paths, test_package = package,     reporter = reporter, load_helpers = load_helpers, env = env,     stop_on_failure = stop_on_failure, stop_on_warning = stop_on_warning,     load_package = load_package, parallel = parallel)
88: test_dir("testthat", package = package, reporter = reporter,     ..., load_package = "installed")
89: test_check("splatter")
An irrecoverable exception occurred. R is aborting now ...
Segmentation fault (core dumped)

Example timings

splatter.Rcheck/splatter-Ex.timings

nameusersystemelapsed
BASiCSEstimate0.0010.0000.000
BASiCSSimulate5.2080.2685.477
addGeneLengths0.3500.0280.379
compareSCEs2.1640.0402.204
diffSCEs2.1930.0362.229
getParam0.0000.0000.001
getParams0.0000.0000.001
kersplatEstimate4.2270.1564.384
kersplatSample1.6800.1161.796
kersplatSetup0.1450.0000.146
kersplatSimulate000
listSims0.0170.0040.021
lun2Estimate0.0000.0010.000
lun2Simulate0.3370.0150.351
lunEstimate0.3990.0120.412
lunSimulate0.3230.0080.330
makeCompPanel000
makeDiffPanel000
makeOverallPanel0.0010.0000.000
mfaEstimate0.0980.0040.101
mfaSimulate1.1890.0281.217
minimiseSCE1.4030.0361.439
mockBulkMatrix0.0010.0000.001
mockBulkeQTL4.9280.2405.169
mockEmpiricalSet2.4030.3282.732
mockGFF0.0020.0000.003
mockVCF0.0960.0000.097
newParams0.0010.0000.002
phenoEstimate0.4650.0080.473
phenoSimulate0.7740.0440.819
scDDEstimate28.987 0.44029.427
scDDSimulate0.0000.0000.001
setParam0.0070.0020.009
setParams0.0140.0080.022
simpleEstimate0.4350.0040.440
simpleSimulate0.5110.0040.516
sparseDCEstimate0.7320.0240.756
sparseDCSimulate1.8370.1802.017
splatEstimate2.6500.0602.711
splatPopEstimate2.6440.0582.703
splatPopQuantNorm0.0250.0000.026
splatPopSimulate0.0000.0000.001
splatPopSimulateMeans000
splatPopSimulateSC0.0000.0010.000
splatSimulate0.7220.0260.749
summariseDiff2.3550.0162.371
zinbEstimate1.9800.0442.024
zinbSimulate0.1470.0160.163