##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:EpiCompare.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings EpiCompare_1.3.4.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.17-bioc/meat/EpiCompare.Rcheck’
* using R Under development (unstable) (2023-03-16 r83985)
* using platform: x86_64-apple-darwin17.0 (64-bit)
* R was compiled by
    Apple clang version 12.0.0 (clang-1200.0.32.29)
    GNU Fortran (GCC) 8.2.0
* running under: macOS Mojave 10.14.6
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘EpiCompare/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘EpiCompare’ version ‘1.3.4’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘EpiCompare’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                             user system elapsed
plot_enrichment            80.867  5.202 118.211
plot_ChIPseeker_annotation 42.606  1.223  56.148
predict_precision_recall   29.588  5.660  12.151
rebin_peaks                13.008  6.714  16.274
plot_precision_recall      16.041  2.911  13.671
EpiCompare                 15.265  1.587  23.318
plot_corr                  11.472  2.379  14.077
compute_corr                6.281  1.796   7.349
plot_chromHMM               6.894  0.917  10.527
liftover_grlist             6.334  0.990  10.078
precision_recall            0.124  0.073  11.735
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 ERROR
Running the tests in ‘tests/testthat.R’ failed.
Last 13 lines of output:
   17.   │                   ├─base (local) handle(...)
   18.   │                   ├─base::withCallingHandlers(...)
   19.   │                   ├─base::withVisible(...)
   20.   │                   └─evaluate:::eval_with_user_handlers(expr, envir, enclos, user_handlers)
   21.   │                     └─base::eval(expr, envir, enclos)
   22.   │                       └─base::eval(expr, envir, enclos)
   23.   └─EpiCompare:::save_output(...)
   24.     └─ggplot2::ggsave(...)
   25.       └─ggplot2 (local) dev(...)
   26.         └─ggplot2 (local) png_dev(..., res = dpi, units = "in")
   27.           └─ragg (local) f(...)
  
  [ FAIL 1 | WARN 5 | SKIP 0 | PASS 92 ]
  Error: Test failures
  Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR
See
  ‘/Users/biocbuild/bbs-3.17-bioc/meat/EpiCompare.Rcheck/00check.log’
for details.

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL EpiCompare
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.3/Resources/library’
* installing *source* package ‘EpiCompare’ ...
** using staged installation
** R
** data
** inst
** byte-compile and prepare package for lazy loading
Warning: replacing previous import ‘Biostrings::pattern’ by ‘grid::pattern’ when loading ‘genomation’
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Warning: replacing previous import ‘Biostrings::pattern’ by ‘grid::pattern’ when loading ‘genomation’
** testing if installed package can be loaded from final location
Warning: replacing previous import ‘Biostrings::pattern’ by ‘grid::pattern’ when loading ‘genomation’
** testing if installed package keeps a record of temporary installation path
* DONE (EpiCompare)

R Under development (unstable) (2023-03-16 r83985) -- "Unsuffered Consequences"
Copyright (C) 2023 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(EpiCompare)

Warning message:
replacing previous import 'Biostrings::pattern' by 'grid::pattern' when loading 'genomation' 
> 
> test_check("EpiCompare")
All EpiCompare features are being used.
WARNING: precision-recall curves cannot be generated when reference=NULL.


processing file: EpiCompare.Rmd
output file: EpiCompare.knit.md

/usr/local/bin/pandoc +RTS -K512m -RTS EpiCompare.knit.md --to html4 --from markdown+autolink_bare_uris+tex_math_single_backslash --output /private/tmp/RtmpvUPaJs/EpiCompare_testthat/EpiCompare.html --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/pagebreak.lua --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/latex-div.lua --self-contained --variable bs3=TRUE --section-divs --table-of-contents --toc-depth 3 --variable toc_float=1 --variable toc_selectors=h1,h2,h3 --variable toc_collapsed=1 --variable toc_smooth_scroll=1 --variable toc_print=1 --template /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmd/h/default.html --no-highlight --variable highlightjs=1 --number-sections --variable theme=bootstrap --css custom.css --mathjax --variable 'mathjax-url=https://mathjax.rstudio.com/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML' --include-in-header /tmp/RtmpvUPaJs/rmarkdown-str114493a7e31e.html --variable code_folding=hide --variable code_menu=1 
[WARNING] This document format requires a nonempty <title> element.
  Please specify either 'title' or 'pagetitle' in the metadata,
  e.g. by using --metadata pagetitle="..." on the command line.
  Falling back to 'EpiCompare.knit'

Output created: /private/tmp/RtmpvUPaJs/EpiCompare_testthat/EpiCompare.html
[1] "Done in 5 min."
All outputs saved to: /tmp/RtmpvUPaJs/EpiCompare_testthat
NOTE: The following EpiCompare features are NOT being used: 
 - upset_plot=
 - stat_plot=
 - chromHMM_plot=
 - chipseeker_plot=
 - enrichment_plot=
 - tss_plot=
 - precision_recall_plot=
 - corr_plot=
 - add_download_button=


processing file: EpiCompare.Rmd
Quitting from lines 279-295 (EpiCompare.Rmd) 
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Removing non-standard chromosomes.
Computing consensus peaks for group: Imperial 
 - 2 files 
 - 1,670-2,707 peaks each
Identified 1,325 consensus peaks from 2 peak files
Computing consensus peaks for group: ENCODE 
 - 1 files 
 - 5,142-5,142 peaks each
WARNING: Cannot compute consensus peaks when group has <2 peak files. Returning original GRanges object instead.
Done computing consensus peaks in 0.01 min.
Removing non-standard chromosomes.
Computing consensus peaks for group: Imperial 
 - 2 files 
 - 1,670-2,707 peaks each
Identified 2,982 consensus peaks from 2 peak files
Computing consensus peaks for group: ENCODE 
 - 1 files 
 - 5,142-5,142 peaks each
WARNING: Cannot compute consensus peaks when group has <2 peak files. Returning original GRanges object instead.
Done computing consensus peaks in 1.24 min.
Standardising peak files in 6,659 bins of 5e+05 bp.
Merging data into matrix.
Binned matrix size: 6,659 x 3
Matrix sparsity: 0.9526
Calculating correlation matrix.
Done computing correlations in 8 seconds.
Saving correlation results ==> /tmp/RtmpvUPaJs/file1144947e0bd01.corr.csv.gz
Standardising peak files in 32,488 bins of 1e+05 bp.
Merging data into matrix.
Binned matrix size: 32,488 x 3
Matrix sparsity: 0.974
Calculating correlation matrix.
Done computing correlations in 8 seconds.
Saving correlation results ==> /tmp/RtmpvUPaJs/file114497398b184.corr.csv.gz
Standardising peak files in 323,636 bins of 1e+04 bp.
Merging data into matrix.
Binned matrix size: 323,636 x 3
Matrix sparsity: 0.9936
Calculating correlation matrix.
Done computing correlations in 11 seconds.
Saving correlation results ==> /tmp/RtmpvUPaJs/file114492dae8c66.corr.csv.gz
Standardising peak files in 647,114 bins of 5,000 bp.
Merging data into matrix.
Binned matrix size: 647,114 x 3
Matrix sparsity: 0.996
Calculating correlation matrix.
Done computing correlations in 15 seconds.
Saving correlation results ==> /tmp/RtmpvUPaJs/file114491e8393f8.corr.csv.gz
--- Running fragment_info() ---
Done.
Writing ==> /tmp/RtmpvUPaJs/processed_results/encode_H3K27ac.narrowPeaks.bed
Writing ==> /tmp/RtmpvUPaJs/processed_results/CnT_H3K27ac.narrowPeaks.bed
Writing ==> /tmp/RtmpvUPaJs/processed_results/CnR_H3K27ac.narrowPeaks.bed
Searching for *.narrowPeaks.bed$ files...
3 matching files identified.
Constructing file names.
Importing files.
Reading narrowPeaks
Reading narrowPeaks
Reading narrowPeaks
3 files retrieved.
Searching for peaks.narrow files...
3 matching files identified.
Constructing file names.
Returning paths.
Searching for peaks.narrow files...
0 matching files identified. Returning NULL.
Writing ==> /tmp/RtmpvUPaJs/processed_results/encode_H3K27ac.narrowPeaks.bed
Preparing chain file.
snapshotDate(): 2023-03-21
loading from cache
require("rtracklayer")
Performing liftover:  hg19  -->  hg38
Removing non-standard chromosomes.
Preparing chain file.
snapshotDate(): 2023-03-21
Preparing chain file.
snapshotDate(): 2023-03-21
loading from cache
Performing liftover:  hg38  -->  hg19
Removing non-standard chromosomes.
loading from cache
Performing liftover:  hg19  -->  mm9
Removing non-standard chromosomes.
NOTE: The following EpiCompare features are NOT being used: 
 - upset_plot=
 - stat_plot=
 - chromHMM_plot=
 - chipseeker_plot=
 - enrichment_plot=
 - tss_plot=
 - precision_recall_plot=
 - corr_plot=
 - add_download_button=


processing file: EpiCompare.Rmd
output file: EpiCompare.knit.md

/usr/local/bin/pandoc +RTS -K512m -RTS EpiCompare.knit.md --to html4 --from markdown+autolink_bare_uris+tex_math_single_backslash --output /private/tmp/RtmpvUPaJs/EpiCompare_test/EpiCompare.html --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/pagebreak.lua --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/latex-div.lua --self-contained --variable bs3=TRUE --section-divs --table-of-contents --toc-depth 3 --variable toc_float=1 --variable toc_selectors=h1,h2,h3 --variable toc_collapsed=1 --variable toc_smooth_scroll=1 --variable toc_print=1 --template /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmd/h/default.html --no-highlight --variable highlightjs=1 --number-sections --variable theme=bootstrap --css custom.css --mathjax --variable 'mathjax-url=https://mathjax.rstudio.com/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML' --include-in-header /tmp/RtmpvUPaJs/rmarkdown-str1144921d8a70b.html --variable code_folding=hide --variable code_menu=1 
[WARNING] This document format requires a nonempty <title> element.
  Please specify either 'title' or 'pagetitle' in the metadata,
  e.g. by using --metadata pagetitle="..." on the command line.
  Falling back to 'EpiCompare.knit'

Output created: /private/tmp/RtmpvUPaJs/EpiCompare_test/EpiCompare.html
[1] "Done in 0.25 min."
All outputs saved to: /tmp/RtmpvUPaJs/EpiCompare_test
NOTE: The following EpiCompare features are NOT being used: 
 - upset_plot=
 - stat_plot=
 - chromHMM_plot=
 - chipseeker_plot=
 - enrichment_plot=
 - tss_plot=
 - precision_recall_plot=
 - corr_plot=
 - add_download_button=


processing file: EpiCompare.Rmd
output file: EpiCompare.knit.md

/usr/local/bin/pandoc +RTS -K512m -RTS EpiCompare.knit.md --to html4 --from markdown+autolink_bare_uris+tex_math_single_backslash --output /private/tmp/RtmpvUPaJs/EpiCompare_test/EpiCompare.html --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/pagebreak.lua --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/latex-div.lua --self-contained --variable bs3=TRUE --section-divs --table-of-contents --toc-depth 3 --variable toc_float=1 --variable toc_selectors=h1,h2,h3 --variable toc_collapsed=1 --variable toc_smooth_scroll=1 --variable toc_print=1 --template /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmd/h/default.html --no-highlight --variable highlightjs=1 --number-sections --variable theme=bootstrap --css custom.css --mathjax --variable 'mathjax-url=https://mathjax.rstudio.com/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML' --include-in-header /tmp/RtmpvUPaJs/rmarkdown-str114493d2cfdc1.html --variable code_folding=hide --variable code_menu=1 
[WARNING] This document format requires a nonempty <title> element.
  Please specify either 'title' or 'pagetitle' in the metadata,
  e.g. by using --metadata pagetitle="..." on the command line.
  Falling back to 'EpiCompare.knit'

Output created: /private/tmp/RtmpvUPaJs/EpiCompare_test/EpiCompare.html
[1] "Done in 0.28 min."
All outputs saved to: /tmp/RtmpvUPaJs/EpiCompare_test
NOTE: The following EpiCompare features are NOT being used: 
 - upset_plot=
 - stat_plot=
 - chromHMM_plot=
 - chipseeker_plot=
 - enrichment_plot=
 - tss_plot=
 - precision_recall_plot=
 - corr_plot=
 - add_download_button=


processing file: EpiCompare.Rmd
output file: EpiCompare.knit.md

/usr/local/bin/pandoc +RTS -K512m -RTS EpiCompare.knit.md --to html4 --from markdown+autolink_bare_uris+tex_math_single_backslash --output /private/tmp/RtmpvUPaJs/EpiCompare_test/testthat_example_Mar_27_2023.html --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/pagebreak.lua --lua-filter /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmarkdown/lua/latex-div.lua --self-contained --variable bs3=TRUE --section-divs --table-of-contents --toc-depth 3 --variable toc_float=1 --variable toc_selectors=h1,h2,h3 --variable toc_collapsed=1 --variable toc_smooth_scroll=1 --variable toc_print=1 --template /Library/Frameworks/R.framework/Versions/4.3/Resources/library/rmarkdown/rmd/h/default.html --no-highlight --variable highlightjs=1 --number-sections --variable theme=bootstrap --css custom.css --mathjax --variable 'mathjax-url=https://mathjax.rstudio.com/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML' --include-in-header /tmp/RtmpvUPaJs/rmarkdown-str114496fe51160.html --variable code_folding=hide --variable code_menu=1 
[WARNING] This document format requires a nonempty <title> element.
  Please specify either 'title' or 'pagetitle' in the metadata,
  e.g. by using --metadata pagetitle="..." on the command line.
  Falling back to 'EpiCompare.knit'

Output created: /private/tmp/RtmpvUPaJs/EpiCompare_test/testthat_example_Mar_27_2023.html
[1] "Done in 0.22 min."
All outputs saved to: /tmp/RtmpvUPaJs/EpiCompare_test
--- Running overlap_heatmap() ---
Warning: fill_diag must =NULL due to a known bug in the package 'heatmaply'.
Genreating precision-recall matrix.
overlap_heatmap(): Done in 1.5s.
--- Running overlap_heatmap() ---
Genreating precision-recall matrix.
overlap_heatmap(): Done in 0.3s.
--- Running overlap_stat_plot() ---
Preparing reference.
Extracting only the first GRanges object from list.
Done.
--- Running overlap_stat_plot() ---
Preparing reference.
Extracting only the first GRanges object from list.
Done.
--- Running peak_info() ---
Done.
Standardising peak files in 647,114 bins of 5,000 bp.
Merging data into matrix.
Binned matrix size: 647,114 x 3
Matrix sparsity: 0.996
Calculating correlation matrix.
Done computing correlations in 14 seconds.
Saving correlation results ==> /tmp/RtmpvUPaJs/file11449414568a3.corr.csv.gz
Threshold=0: Filtering peaks
Threshold=0.05: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.1: Filtering peaks
Threshold=0.15: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.25: Filtering peaks
Threshold=0.2: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.3: Filtering peaks
Threshold=0.35: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.4: Filtering peaks
Threshold=0.45: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.5: Filtering peaks
Threshold=0.55: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.65: Filtering peaks
Threshold=0.6: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.75: Filtering peaks
Threshold=0.7: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.8: Filtering peaks
Threshold=0.85: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Threshold=0.9: Filtering peaks
Threshold=0.95: Filtering peaks
Computing precision-recall results.
Computing precision-recall results.
Reformatting precision-recall data.
Saving precision-recall results ==> /tmp/RtmpvUPaJs/file114495ce45aa0precision_recall.csv
Plotting precision-recall curve.
Plotting F1.
Making predictions for peaklist1: CnR_H3K27ac
Making predictions for peaklist2: encode_H3K27ac
+ Predicting recall from 10 precision values.
+ Predicting precision from 10 recall values.
Making predictions for peaklist1: CnT_H3K27ac
Making predictions for peaklist2: encode_H3K27ac
+ Predicting recall from 10 precision values.
+ Predicting precision from 10 recall values.
WARNING: 'CnT_missing' missing threshold col, will be excluded from precision-recall calculations.
Standardising peak files in 647,114 bins of 5,000 bp.
Merging data into matrix.
Converting to sparse matrix.
Binned matrix size: 647,114 x 2
Matrix sparsity: 0.9968
WARNING: 'CnT_missing' missing threshold col, will be excluded from precision-recall calculations.
Standardising peak files in 416,959 bins of 5,000 bp.
Merging data into matrix.
Converting to sparse matrix.
Binned matrix size: 416,959 x 2
Matrix sparsity: 0.995
--- Running tss_plot() ---
>> Running bootstrapping for tag matrix...		 2023-03-27 01:37:16 
>> Running bootstrapping for tag matrix...		 2023-03-27 01:37:16 
Done.
--- Running width_boxplot() ---
Done.
[ FAIL 1 | WARN 5 | SKIP 0 | PASS 92 ]

══ Failed tests ════════════════════════════════════════════════════════════════
── Error ('test-EpiCompare.R:57:3'): All options FALSE, correct outputs generated ──
Error in `f(...)`: Graphics API version mismatch
Backtrace:
     ▆
  1. └─EpiCompare::EpiCompare(...) at test-EpiCompare.R:57:2
  2.   ├─rmarkdown::render(...)
  3.   │ └─knitr::knit(knit_input, knit_output, envir = envir, quiet = quiet)
  4.   │   └─knitr:::process_file(text, output)
  5.   │     ├─base::withCallingHandlers(...)
  6.   │     ├─knitr:::process_group(group)
  7.   │     └─knitr:::process_group.block(group)
  8.   │       └─knitr:::call_block(x)
  9.   │         └─knitr:::block_exec(params)
 10.   │           └─knitr:::eng_r(options)
 11.   │             ├─knitr:::in_input_dir(...)
 12.   │             │ └─knitr:::in_dir(input_dir(), expr)
 13.   │             └─knitr (local) evaluate(...)
 14.   │               └─evaluate::evaluate(...)
 15.   │                 └─evaluate:::evaluate_call(...)
 16.   │                   ├─evaluate (local) timing_fn(...)
 17.   │                   ├─base (local) handle(...)
 18.   │                   ├─base::withCallingHandlers(...)
 19.   │                   ├─base::withVisible(...)
 20.   │                   └─evaluate:::eval_with_user_handlers(expr, envir, enclos, user_handlers)
 21.   │                     └─base::eval(expr, envir, enclos)
 22.   │                       └─base::eval(expr, envir, enclos)
 23.   └─EpiCompare:::save_output(...)
 24.     └─ggplot2::ggsave(...)
 25.       └─ggplot2 (local) dev(...)
 26.         └─ggplot2 (local) png_dev(..., res = dpi, units = "in")
 27.           └─ragg (local) f(...)

[ FAIL 1 | WARN 5 | SKIP 0 | PASS 92 ]
Error: Test failures
Execution halted