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CHECK report for GGtools on merida1

This page was generated on 2021-05-06 12:35:07 -0400 (Thu, 06 May 2021).

To the developers/maintainers of the GGtools package:
Please make sure to use the following settings in order to reproduce any error or warning you see on this page.
Package 739/1974HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
GGtools 5.26.0  (landing page)
VJ Carey
Snapshot Date: 2021-05-05 14:51:38 -0400 (Wed, 05 May 2021)
URL: https://git.bioconductor.org/packages/GGtools
Branch: RELEASE_3_12
Last Commit: e3aed73
Last Changed Date: 2020-10-27 10:29:23 -0400 (Tue, 27 Oct 2020)
malbec1Linux (Ubuntu 18.04.5 LTS) / x86_64  OK    OK    ERROR  
tokay1Windows Server 2012 R2 Standard / x64  OK    OK    ERROR    OK  
merida1macOS 10.14.6 Mojave / x86_64  OK    OK    ERROR    OK  

Summary

Package: GGtools
Version: 5.26.0
Command: /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD check --install=check:GGtools.install-out.txt --library=/Library/Frameworks/R.framework/Versions/Current/Resources/library --no-vignettes --timings GGtools_5.26.0.tar.gz
StartedAt: 2021-05-06 02:14:39 -0400 (Thu, 06 May 2021)
EndedAt: 2021-05-06 02:30:56 -0400 (Thu, 06 May 2021)
EllapsedTime: 976.4 seconds
RetCode: 1
Status:   ERROR  
CheckDir: GGtools.Rcheck
Warnings: NA

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD check --install=check:GGtools.install-out.txt --library=/Library/Frameworks/R.framework/Versions/Current/Resources/library --no-vignettes --timings GGtools_5.26.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck’
* using R version 4.0.5 (2021-03-31)
* using platform: x86_64-apple-darwin17.0 (64-bit)
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘GGtools/DESCRIPTION’ ... OK
* this is package ‘GGtools’ version ‘5.26.0’
* checking package namespace information ... OK
* checking package dependencies ... NOTE
Package which this enhances but not available for checking: ‘MatrixEQTL’
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘GGtools’ can be installed ... WARNING
Found the following significant warnings:
  Warning: Package 'GGBase' is deprecated and will be removed from Bioconductor
  Warning: Package 'GGtools' is deprecated and will be removed from Bioconductor
See ‘/Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/00install.out’ for details.
* checking installed package size ... NOTE
  installed size is 72.9Mb
  sub-directories of 1Mb or more:
    R       2.0Mb
    data   27.0Mb
    parts   2.0Mb
    pup     2.0Mb
    rdas   10.3Mb
    vcf    28.8Mb
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
Malformed Description field: should contain one or more complete sentences.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
'library' or 'require' call to 'Homo.sapiens' which was already attached by Depends.
  Please remove these calls from your code.
Packages in Depends field not imported from:
  'Homo.sapiens' 'parallel'
  These packages need to be imported from (in the NAMESPACE file)
  for when this namespace is loaded but not attached.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
plot,gwSnpScreenResult-character: warning in axis(3, at =
  genePosition(x@gene, annlib = x@annotation), col = "red", lwd = 2,
  label = " "): partial argument match of 'label' to 'labels'
.summarize: no visible binding for global variable 'npc'
.summarize: no visible binding for global variable 'maf'
.summarize: no visible binding for global variable 'radiusUsed'
.summarize: no visible binding for global variable 'excl'
.transTab: no visible global function definition for 'snpsBySeqname'
SnpMatrixCisToSummex: no visible global function definition for
  'rowRanges'
add878: no visible binding for global variable 'hmm878'
addcadd: no visible binding for global variable 'bindcadd'
addcadd: no visible global function definition for '%dopar%'
addcadd: no visible global function definition for 'foreach'
addcadd: no visible binding for global variable 'x'
addgwhit: no visible binding for global variable 'gwastagger'
addgwhit: no visible global function definition for 'overlapsAny'
appraise : .redu.fdr: no visible global function definition for
  'setkey'
appraise : .redu.fdr: no visible binding for global variable 'snp'
appraise : .redu.fdr: no visible binding for global variable '.N'
appraise : .redu.fdr : <anonymous>: no visible global function
  definition for 'setkeyv'
appraise : .redu.fdr : <anonymous>: no visible binding for global
  variable '.N'
appraise : .discmods: no visible global function definition for
  '%dopar%'
appraise : .discmods: no visible global function definition for
  'foreach'
buildConfList : z : <anonymous>: no visible binding for global variable
  'pl'
cgff2dt: no visible global function definition for '%dopar%'
cgff2dt: no visible global function definition for 'foreach'
cgff2dt: no visible global function definition for 'as.data.table'
cgff2dt: no visible binding for global variable 'hmm878'
cgff2dt: no visible global function definition for 'overlapsAny'
cgff2dt: no visible binding for global variable 'gwastagger'
cisAssoc: no visible global function definition for 'rowRanges'
cisAssoc: no visible global function definition for 'assays'
cisAssoc: no visible global function definition for 'colData'
cisAssoc: no visible binding for global variable 'chi.squared'
ciseqByCluster : <anonymous>: no visible global function definition for
  'detectCores'
ciseqByCluster: no visible binding for '<<-' assignment to 'firstHalf'
ciseqByCluster: no visible binding for '<<-' assignment to 'secondHalf'
ciseqByCluster: no visible binding for '<<-' assignment to 'firstThird'
ciseqByCluster: no visible binding for '<<-' assignment to 'lastThird'
ciseqByCluster: no visible binding for '<<-' assignment to 'midThird'
ciseqByCluster : setupSplit : <anonymous>: no visible binding for
  global variable 'mclapply'
ciseqByCluster: no visible binding for '<<-' assignment to
  'runOneSplit'
ciseqByCluster : <anonymous>: no visible binding for global variable
  'firstHalf'
ciseqByCluster : <anonymous> : cr2gff: no visible global function
  definition for 'ranges<-'
ciseqByCluster : <anonymous> : cr2gff: no visible global function
  definition for 'export.gff3'
ciseqByCluster: no visible binding for global variable 'firstThird'
ciseqByCluster: no visible binding for global variable 'midThird'
ciseqByCluster: no visible binding for global variable 'lastThird'
ciseqByCluster : <anonymous>: no visible global function definition for
  'runOneSplit'
eqBox: no visible global function definition for 'assay'
eqDesc: no visible global function definition for 'assay'
eqsens_dt: no visible global function definition for 'setnames'
eqsens_dt: no visible global function definition for '%dopar%'
eqsens_dt: no visible global function definition for 'foreach'
eqsens_dt: no visible binding for global variable 'curp'
eqtlTests.me: no visible binding for global variable 'modelLINEAR'
eqtlTests.me: no visible binding for global variable 'SlicedData'
eqtlTests.me: no visible binding for global variable
  'Matrix_eQTL_engine'
eqtlTests.meText: no visible binding for global variable 'modelLINEAR'
eqtlTests.meText: no visible binding for global variable 'SlicedData'
eqtlTests.meText: no visible binding for global variable
  'Matrix_eQTL_engine'
fplot: no visible global function definition for 'forestplot'
genemodel: no visible global function definition for 'select'
genemodel: no visible binding for global variable 'Homo.sapiens'
getAsSlicedData: no visible binding for global variable 'target'
getCisMap: no visible global function definition for 'snpsBySeqname'
get_probechunks: no visible global function definition for 'select'
inflammFilter: no visible binding for global variable 'gwrngs'
inflammFilter: no visible global function definition for 'overlapsAny'
makeSeqinfo: no visible binding for global variable 'hg19.si.df'
plotsens: no visible binding for global variable 'mafs'
plotsens: no visible binding for global variable 'value'
plotsens: no visible binding for global variable 'FDR'
pullHits: no visible global function definition for 'ranges<-'
richNull : <anonymous>: no visible global function definition for
  'bindmaf'
simpleTiling: no visible binding for global variable 'Homo.sapiens'
simpleTiling: no visible global function definition for 'tileGenome'
topKfeats: no visible binding for global variable 'i1'
topKfeats: no visible binding for global variable 'i2'
tscan2df: no visible global function definition for '%dopar%'
tscan2df: no visible global function definition for 'foreach'
tscan2df: no visible binding for global variable 'i'
tscan2gr: no visible global function definition for '%dopar%'
tscan2gr: no visible global function definition for 'foreach'
tscan2gr: no visible binding for global variable 'i'
waldtests : <anonymous>: no visible global function definition for
  'wald.test'
plot,gwSnpScreenResult-character: no visible global function definition
  for 'snpcount'
plot,gwSnpScreenResult-character: no visible global function definition
  for 'snpsBySeqname'
Undefined global functions or variables:
  %dopar% .N FDR Homo.sapiens Matrix_eQTL_engine SlicedData
  as.data.table assay assays bindcadd bindmaf chi.squared colData curp
  detectCores excl export.gff3 firstHalf firstThird foreach forestplot
  gwastagger gwrngs hg19.si.df hmm878 i i1 i2 lastThird maf mafs
  mclapply midThird modelLINEAR npc overlapsAny pl radiusUsed ranges<-
  rowRanges runOneSplit select setkey setkeyv setnames snp snpcount
  snpsBySeqname target tileGenome value wald.test x
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... NOTE
Package unavailable to check Rd xrefs: ‘MatrixEQTL’
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking sizes of PDF files under ‘inst/doc’ ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
            user system elapsed
cisAssoc  53.038  1.224  54.336
eqtlTests  8.873  0.533   9.426
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘cis.R’
  Running ‘eqvgwst.R’
  Running ‘test.meqtlTests.R’
  Running ‘test.meta.trans.R’
  Running ‘testCisMap.R’
  Running ‘testTrans.R’
 ERROR
Running the tests in ‘tests/testTrans.R’ failed.
Last 13 lines of output:
  > schrpref(tconf) = "ch"
  > exFilter(tconf) = function(x)x
  > gchrpref = ""
  > batchsize(tconf) = 200L
  > 
  > suppressPackageStartupMessages(library(GGtools))
  > 
  > t1 = transScores(tconf)
  Loading required package: illuminaHumanv1.db
  
  opening ff /Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/tests/cisScratch22/tsc_20_chr22.ff
  2opening ff /Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/tests/cisScratch22/tsctmp2_chr22.ff
  Error in get(".rambytes") : object '.rambytes' not found
  Calls: transScores -> updateKfeats -> chunk -> chunk.default -> get
  Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 1 WARNING, 6 NOTEs
See
  ‘/Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/00check.log’
for details.


Installation output

GGtools.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Versions/Current/Resources/bin/R CMD INSTALL GGtools
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.0/Resources/library’
* installing *source* package ‘GGtools’ ...
** using staged installation
** R
** data
** inst
** byte-compile and prepare package for lazy loading
Warning message:
Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13 
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Warning: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13
Warning: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13
** testing if installed package can be loaded from final location
Warning: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13
Warning: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13
** testing if installed package keeps a record of temporary installation path
* DONE (GGtools)

Tests output

GGtools.Rcheck/tests/cis.Rout


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> 
> suppressPackageStartupMessages(library(GGtools))
Warning messages:
1: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13 
2: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13 
> 
> # configure
>    cc = new("CisConfig")
>    chrnames(cc) = "21"
>    genome(cc) = "hg19"
>    nperm(cc) = 2L
>    lkp = try(library(parallel))
>    if (!inherits(lkp, "try-error")) {
+       nc = min(10, detectCores())
+       options(mc.cores=nc)
+       geneApply(cc) = mclapply
+       }
>    estimates(cc) = FALSE
>    set.seed(1234)
> #   system.time(f1 <- cisScores( cc ))
>  #
>  # demonstrate adding annotation on chromatin state and gwas status
>  #
>  eprops = function(ans) {
+  #
+  # only adds fields to values() of the input
+  #
+   data(hmm878)
+   ac = as.character
+   eqr = GRanges(ac(seqnames(ans)), IRanges(ans$snplocs, width=1))
+   fo = findOverlaps(eqr, hmm878)
+   chromcat878 = factor(rep("none", length(ans)), levels=c(unique(hmm878$name), "none"))
+   chromcat878[ queryHits(fo) ] = factor(hmm878$name[subjectHits(fo)])
+   ans$chromcat878 = chromcat878
+  
+   if (require(gwascat)) {
+     data(gwastagger)
+     isgwashit = 1*(overlapsAny(eqr, gwastagger) | ans$snp %in% gwastagger$tagid) # allow match by loc or name
+     ans$isgwashit = isgwashit
+     }
+   ans
+  }
>  extraProps(cc) = eprops
>  set.seed(1234)
>  rhs(cc) = ~1-1
> if (.Platform$OS.type != "windows") {
+  (f2 <- cisScores( cc ))
+  isTRUE(sum(f2$fdr < 0.05) > 0)  # can change with annotation or location changes, check serialized results if necessary
+ }
get data...build map...

Attaching package: 'Biostrings'

The following object is masked from 'package:base':

    strsplit

NOTE: expanding gene ranges by radius 50000 leads to negative start positions that are reset to 1.
run smFilter...filter probes in map...tests...get data...build map...run smFilter...filter probes in map...tests...get data...build map...run smFilter...filter probes in map...tests...Loading required package: gwascat
gwascat loaded.  Use makeCurrentGwascat() to extract current image.
 from EBI.  The data folder of this package has some legacy extracts.
[1] TRUE
> TRUE
[1] TRUE
> 
> proc.time()
   user  system elapsed 
113.131   9.515 107.894 

GGtools.Rcheck/tests/eqvgwst.Rout


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> 
> # april 2011/jan 2012
> # compares gwSnpTests to eqtlTests
> library(GGtools)
Loading required package: GGBase
Loading required package: snpStats
Loading required package: survival
Loading required package: Matrix
Loading required package: data.table
Loading required package: parallel
Loading required package: Homo.sapiens
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which.max, which.min

Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: IRanges
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:data.table':

    first, second

The following object is masked from 'package:Matrix':

    expand

The following object is masked from 'package:base':

    expand.grid


Attaching package: 'IRanges'

The following object is masked from 'package:data.table':

    shift

Loading required package: OrganismDbi
Loading required package: GenomicFeatures
Loading required package: GenomeInfoDb
Loading required package: GenomicRanges
Loading required package: GO.db

Loading required package: org.Hs.eg.db

Loading required package: TxDb.Hsapiens.UCSC.hg19.knownGene

Attaching package: 'GGtools'

The following object is masked from 'package:stats':

    getCall

Warning messages:
1: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13 
2: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13 
> hmceuB36.2021 <- getSS("GGtools", c("20"))
> library(illuminaHumanv1.db)

> cp = get("CPNE1", revmap(illuminaHumanv1SYMBOL))
> hcp = hmceuB36.2021[ probeId(cp), ]
> t1 = gwSnpTests(genesym("CPNE1")~male, hcp)
> pick = as(t1@.Data[[1]], "data.frame")[22101:22115,]
> rsids = rownames(pick)[!is.na(pick[,1])]
> csq = pick[rsids,1]
> names(csq) = rsids
> fi = tempfile()
> if (file.exists(fi)) unlink(fi, recursive=TRUE)
> t2 = eqtlTests(hcp, ~male, targdir=fi)
> sco = t2[rsids,][,1]
> unlink(fi, recursive=TRUE)
> comp = (sco-trunc(100*csq,0)/100)/sco
> (!(max(abs(comp)) > .01))
[1] TRUE
> 
> 
> proc.time()
   user  system elapsed 
 26.148   1.496  29.122 

GGtools.Rcheck/tests/test.meqtlTests.Rout


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(GGtools)
Loading required package: GGBase
Loading required package: snpStats
Loading required package: survival
Loading required package: Matrix
Loading required package: data.table
Loading required package: parallel
Loading required package: Homo.sapiens
Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which.max, which.min

Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.

Loading required package: IRanges
Loading required package: S4Vectors

Attaching package: 'S4Vectors'

The following objects are masked from 'package:data.table':

    first, second

The following object is masked from 'package:Matrix':

    expand

The following object is masked from 'package:base':

    expand.grid


Attaching package: 'IRanges'

The following object is masked from 'package:data.table':

    shift

Loading required package: OrganismDbi
Loading required package: GenomicFeatures
Loading required package: GenomeInfoDb
Loading required package: GenomicRanges
Loading required package: GO.db

Loading required package: org.Hs.eg.db

Loading required package: TxDb.Hsapiens.UCSC.hg19.knownGene

Attaching package: 'GGtools'

The following object is masked from 'package:stats':

    getCall

Warning messages:
1: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13 
2: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13 
> library(ff)
Loading required package: bit

Attaching package: 'bit'

The following object is masked from 'package:data.table':

    setattr

The following object is masked from 'package:base':

    xor

Attaching package ff
- getOption("fftempdir")=="/tmp/RtmpS4hJjt/ff"

- getOption("ffextension")=="ff"

- getOption("ffdrop")==TRUE

- getOption("fffinonexit")==TRUE

- getOption("ffpagesize")==65536

- getOption("ffcaching")=="mmnoflush"  -- consider "ffeachflush" if your system stalls on large writes

- getOption("ffbatchbytes")==16777216 -- consider a different value for tuning your system

- getOption("ffmaxbytes")==536870912 -- consider a different value for tuning your system


Attaching package: 'ff'

The following objects are masked from 'package:utils':

    write.csv, write.csv2

The following objects are masked from 'package:base':

    is.factor, is.ordered

> 
> tenOn2021 =
+ c( "GI_4557248-S",  "GI_15451784-S", "GI_4557678-S", "GI_9951914-S", "GI_21327679-S",
+  "GI_7669476-I", "GI_7669478-A", "GI_4557290-I", "GI_4557294-A", "GI_41406053-S")
> 
> c22 = getSS("GGdata", "22")
> c22 = c22[probeId(tenOn2021),]
> 
> e1 = eqtlTests(c22, ~1, targdir = "ooo")
> m1 = meqtlTests(list(c22, c22), list(~1, ~1), targdir = "ooobb")
> 
> ae = as.ram(e1@fffile)
opening ff /Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/tests/ooo/foo_chr22.ff
> am = as.ram(m1@fffile)
> all.equal(as.numeric(ae)*2 ,as.numeric(am) )
[1] TRUE
> 
> system("rm -rf ooo")
> system("rm -rf ooobb")
> 
> proc.time()
   user  system elapsed 
 32.054   1.531  34.963 

GGtools.Rcheck/tests/test.meta.trans.Rout


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> 
> heavyTest = function() {
+ library(GGtools)
+ 
+ # verifies that transScores agrees with snp.rhs.tests to obtain best
+ # trans scores
+ 
+ tenOn2021 = 
+ c( "GI_4557248-S",  "GI_15451784-S", "GI_4557678-S", "GI_9951914-S", "GI_21327679-S",
+  "GI_7669476-I", "GI_7669478-A", "GI_4557290-I", "GI_4557294-A", "GI_41406053-S") 
+ 
+ suppressPackageStartupMessages(library(GGtools))
+ 
+ mt1 = meta.transScores(c("GGdata", "GGdata"), rhs=list(~1, ~1), snpchr="22", chrnames=as.character(c(20,21)),
+ #
+ # all tests are trans, to verify buffering approach
+ #
+         radius = 2e+06,  K=4, targdir="uiu2",
+     probesToKeep = tenOn2021, batchsize = 200, 
+     geneannopk = "illuminaHumanv1.db", 
+     snpannopk = "SNPlocs.Hsapiens.dbSNP.20111119", gchrpref = "", SMFilterList = list( function(x) x[probeId(tenOn2021),],
+          function(x) x[probeId(tenOn2021), ]),
+     schrpref = "ch", exFilter = list( function(x) x, function(x) x)) 
+ 
+ transTab(mt1)
+ }
> 
> proc.time()
   user  system elapsed 
  0.261   0.061   0.302 

GGtools.Rcheck/tests/testCisMap.Rout


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> if (.Platform$OS.type != "windows") {
+ t20 = GGtools:::getCisMap()
+ 
+ NL = GGtools:::namelist(t20)
+ 
+ NL1 = NL[[1]]
+ 
+ t20sl = t20@snplocs[NL1]
+ 
+ probe1 = names(NL)[1]
+ 
+ TARG = t20@generanges[probe1]-50000
+ 
+ d = distance(TARG, t20sl)
+ 
+ all(d <= 50000)
+ } else TRUE

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:parallel':

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which.max, which.min

Welcome to Bioconductor

    Vignettes contain introductory material; view with
    'browseVignettes()'. To cite Bioconductor, see
    'citation("Biobase")', and for packages 'citation("pkgname")'.


Attaching package: 'S4Vectors'

The following object is masked from 'package:base':

    expand.grid




Attaching package: 'Biostrings'

The following object is masked from 'package:base':

    strsplit

NOTE: expanding gene ranges by radius 50000 leads to negative start positions that are reset to 1.
[1] TRUE
> 
> proc.time()
   user  system elapsed 
 54.998   2.943  59.410 

GGtools.Rcheck/tests/testTrans.Rout.fail


R version 4.0.5 (2021-03-31) -- "Shake and Throw"
Copyright (C) 2021 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin17.0 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> # verifies that transScores agrees with snp.rhs.tests to obtain best
> # trans scores
> 
> suppressPackageStartupMessages(library(GGtools))
Warning messages:
1: Package 'GGBase' is deprecated and will be removed from Bioconductor
  version 3.13 
2: Package 'GGtools' is deprecated and will be removed from Bioconductor
  version 3.13 
> 
> tenOn2021 = 
+ c( "GI_4557248-S",  "GI_15451784-S", "GI_4557678-S", "GI_9951914-S", "GI_21327679-S",
+  "GI_7669476-I", "GI_7669478-A", "GI_4557290-I", "GI_4557294-A", "GI_41406053-S") 
> 
> tconf = new("TransConfig")
> radius(tconf) = 2000000L
> smpack(tconf) = "GGdata"
> rhs(tconf) = ~1
> snpchr(tconf) = "22"  # we get scores for all SNP on this chrom
> chrnames(tconf) = c("20", "21")
> gbufsize(tconf) = 4L
> smFilter(tconf) = function(x) x[probeId(tenOn2021),]
> snpannopk(tconf) = snplocsDefault()
> schrpref(tconf) = "ch"
> exFilter(tconf) = function(x)x
> gchrpref = ""
> batchsize(tconf) = 200L
> 
> suppressPackageStartupMessages(library(GGtools))
> 
> t1 = transScores(tconf)
Loading required package: illuminaHumanv1.db

opening ff /Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/tests/cisScratch22/tsc_20_chr22.ff
2opening ff /Users/biocbuild/bbs-3.12-bioc/meat/GGtools.Rcheck/tests/cisScratch22/tsctmp2_chr22.ff
Error in get(".rambytes") : object '.rambytes' not found
Calls: transScores -> updateKfeats -> chunk -> chunk.default -> get
Execution halted

Example timings

GGtools.Rcheck/GGtools-Ex.timings

nameusersystemelapsed
All.cis0.0010.0010.001
CisConfig-class0.0020.0010.003
EqAppr-class0.0010.0010.002
GGtools-package000
TransConfig-class0.0010.0010.002
b10.0700.0050.076
best.cis.eQTLs0.0010.0000.001
best.trans.eQTLs0.0000.0010.000
bindmaf0.0000.0000.001
cgff2dt0.0170.0020.017
cisAssoc53.038 1.22454.336
cisRun-class0.0010.0000.001
ciseqByCluster0.0010.0000.000
collectBest0.0000.0000.001
concatCis000
eqBox3.0930.0733.171
eqsens_dt0.0000.0000.001
eqtlTests8.8730.5339.426
eqtlTests.me0.0010.0000.001
eqtlTestsManager-class0.0010.0010.001
ex2.3360.0372.376
getCisMap0.0000.0010.000
gwSnpTests2.8100.0472.860
hmm8780.6090.0170.626
pifdr0.9820.0961.081
qqhex0.7400.0160.762
sampsInVCF0.0770.0030.081
sensiCisInput-class0.0000.0010.001
sensiCisOutput-class0.0010.0000.001
simpleTiling0.0010.0000.001
snplocsDefault000
strMultPop0.0770.0090.087
transManager-class0.0010.0010.001
transScores0.0010.0000.000
vcf2sm0.1310.0330.166