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This is the development version of cleaver; for the stable release version, see cleaver.

Cleavage of Polypeptide Sequences

Bioconductor version: Development (3.19)

In-silico cleavage of polypeptide sequences. The cleavage rules are taken from: http://web.expasy.org/peptide_cutter/peptidecutter_enzymes.html

Author: Sebastian Gibb [aut, cre]

Maintainer: Sebastian Gibb <mail at sebastiangibb.de>

Citation (from within R, enter citation("cleaver")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

In-silico cleavage of polypeptides HTML R Script
Reference Manual PDF


biocViews Proteomics, Software
Version 1.41.2
In Bioconductor since BioC 2.13 (R-3.0) (10.5 years)
License GPL (>= 3)
Depends R (>= 3.0.0), methods, Biostrings(>= 1.29.8)
Imports S4Vectors, IRanges
System Requirements
URL https://github.com/sgibb/cleaver/
Bug Reports https://github.com/sgibb/cleaver/issues/
See More
Suggests testthat (>= 0.8), knitr, BiocStyle(>= 0.0.14), rmarkdown, BRAIN, UniProt.ws(>= 2.36.5)
Linking To
Depends On Me
Imports Me ProteoDisco, synapter
Suggests Me RforProteomics
Links To Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package cleaver_1.41.2.tar.gz
Windows Binary cleaver_1.41.2.zip (64-bit only)
macOS Binary (x86_64) cleaver_1.41.2.tgz
macOS Binary (arm64) cleaver_1.41.2.tgz
Source Repository git clone https://git.bioconductor.org/packages/cleaver
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/cleaver
Bioc Package Browser https://code.bioconductor.org/browse/cleaver/
Package Short Url https://bioconductor.org/packages/cleaver/
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