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This is the development version of oppar; for the stable release version, see oppar.

Outlier profile and pathway analysis in R

Bioconductor version: Development (3.19)

The R implementation of mCOPA package published by Wang et al. (2012). Oppar provides methods for Cancer Outlier profile Analysis. Although initially developed to detect outlier genes in cancer studies, methods presented in oppar can be used for outlier profile analysis in general. In addition, tools are provided for gene set enrichment and pathway analysis.

Author: Chenwei Wang [aut], Alperen Taciroglu [aut], Stefan R Maetschke [aut], Colleen C Nelson [aut], Mark Ragan [aut], Melissa Davis [aut], Soroor Hediyeh zadeh [cre], Momeneh Foroutan [ctr]

Maintainer: Soroor Hediyeh zadeh <hediyehzadeh.s at wehi.edu.au>

Citation (from within R, enter citation("oppar")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

OPPAR: Outlier Profile and Pathway Analysis in R HTML R Script
Reference Manual PDF


biocViews GeneExpression, GeneSetEnrichment, Pathways, Software, SystemsBiology
Version 1.31.0
In Bioconductor since BioC 3.3 (R-3.3) (8 years)
License GPL-2
Depends R (>= 3.3)
Imports Biobase, methods, GSEABase, GSVA
System Requirements
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Suggests knitr, rmarkdown, limma, org.Hs.eg.db, GO.db, snow, parallel
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Follow Installation instructions to use this package in your R session.

Source Package oppar_1.31.0.tar.gz
Windows Binary oppar_1.31.0.zip
macOS Binary (x86_64) oppar_1.31.0.tgz
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/oppar
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/oppar
Bioc Package Browser https://code.bioconductor.org/browse/oppar/
Package Short Url https://bioconductor.org/packages/oppar/
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