RNAAgeCalc

DOI: 10.18129/B9.bioc.RNAAgeCalc    

This is the development version of RNAAgeCalc; for the stable release version, see RNAAgeCalc.

A multi-tissue transcriptional age calculator

Bioconductor version: Development (3.12)

It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

Author: Xu Ren [aut, cre], Pei Fen Kuan [aut]

Maintainer: Xu Ren <xuren2120 at gmail.com>

Citation (from within R, enter citation("RNAAgeCalc")):

Installation

To install this package, start R (version "4.0") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("RNAAgeCalc")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RNAAgeCalc")

 

HTML R Script RNAAgeCalc
PDF   Reference Manual
Text   NEWS

Details

biocViews GeneExpression, RNASeq, Software
Version 1.1.2
In Bioconductor since BioC 3.11 (R-4.0) (< 6 months)
License GPL-2
Depends R (>= 3.6)
Imports ggplot2, recount, impute, AnnotationDbi, org.Hs.eg.db, stats, SummarizedExperiment, methods
LinkingTo
Suggests knitr, rmarkdown, testthat
SystemRequirements
Enhances
URL https://github.com/reese3928/RNAAgeCalc
BugReports https://github.com/reese3928/RNAAgeCalc/issues
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RNAAgeCalc_1.1.2.tar.gz
Windows Binary RNAAgeCalc_1.1.2.zip (32- & 64-bit)
macOS 10.13 (High Sierra) RNAAgeCalc_1.1.2.tgz
Source Repository git clone https://git.bioconductor.org/packages/RNAAgeCalc
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RNAAgeCalc
Package Short Url https://bioconductor.org/packages/RNAAgeCalc/
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