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This is the development version of EmpiricalBrownsMethod; for the stable release version, see EmpiricalBrownsMethod.

Uses Brown's method to combine p-values from dependent tests

Bioconductor version: Development (3.19)

Combining P-values from multiple statistical tests is common in bioinformatics. However, this procedure is non-trivial for dependent P-values. This package implements an empirical adaptation of Brown’s Method (an extension of Fisher’s Method) for combining dependent P-values which is appropriate for highly correlated data sets found in high-throughput biological experiments.

Author: William Poole

Maintainer: David Gibbs <dgibbs at>

Citation (from within R, enter citation("EmpiricalBrownsMethod")):


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# The following initializes usage of Bioc devel


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biocViews GeneExpression, Pathways, Software, StatisticalMethod
Version 1.31.0
In Bioconductor since BioC 3.3 (R-3.3) (8 years)
License MIT + file LICENSE
Depends R (>= 3.2.0)
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