CatsCradle

This is the development version of CatsCradle; to use it, please install the devel version of Bioconductor.

This package provides methods for analysing spatial transcriptomics data and for discovering gene clusters


Bioconductor version: Development (3.20)

This package addresses two broad areas. It allows for in-depth analysis of spatial transcriptomic data by identifying tissue neighbourhoods. These are contiguous regions of tissue surrounding individual cells. 'CatsCradle' allows for the categorisation of neighbourhoods by the cell types contained in them and the genes expressed in them. In particular, it produces Seurat objects whose individual elements are neighbourhoods rather than cells. In addition, it enables the categorisation and annotation of genes by producing Seurat objects whose elements are genes.

Author: Anna Laddach [aut] , Michael Shapiro [aut, cre]

Maintainer: Michael Shapiro <michael.shapiro at crick.ac.uk>

Citation (from within R, enter citation("CatsCradle")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("CatsCradle")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CatsCradle")
CatsCradle HTML R Script
CatsCradle Example Data HTML R Script
CatsCradle Quick Start HTML R Script
CatsCradle SingleCellExperiment Quick Start HTML R Script
CatsCradle Spatial Vignette HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews BiologicalQuestion, GeneExpression, SingleCell, Software, Spatial, StatisticalMethod, Transcriptomics
Version 0.99.15
In Bioconductor since BioC 3.20 (R-4.4)
License MIT + file LICENSE
Depends R (>= 4.4.0)
Imports Seurat (>= 5.0.1), ggplot2, networkD3, stringr, pracma, reshape2, rdist, igraph, geometry, Rfast, data.table, abind, pheatmap, EBImage, S4Vectors, SeuratObject, SingleCellExperiment, SpatialExperiment, Matrix, methods, SummarizedExperiment, msigdbr
System Requirements
URL https://github.com/AnnaLaddach/CatsCradle
Bug Reports https://github.com/AnnaLaddach/CatsCradle/issues
See More
Suggests fossil, interp, knitr, BiocStyle, tictoc
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CatsCradle_0.99.15.tar.gz
Windows Binary CatsCradle_0.99.15.zip
macOS Binary (x86_64) CatsCradle_0.99.15.tgz
macOS Binary (arm64) CatsCradle_0.99.15.tgz
Source Repository git clone https://git.bioconductor.org/packages/CatsCradle
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/CatsCradle
Bioc Package Browser https://code.bioconductor.org/browse/CatsCradle/
Package Short Url https://bioconductor.org/packages/CatsCradle/
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