airpart
Differential cell-type-specific allelic imbalance
Bioconductor version: Release (3.19)
Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.
Author: Wancen Mu [aut, cre] , Michael Love [aut, ctb]
Maintainer: Wancen Mu <wancen at live.unc.edu>
citation("airpart")
):
Installation
To install this package, start R (version "4.4") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("airpart")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("airpart")
Differential allelic imbalance with airpart | HTML | R Script |
Reference Manual | ||
NEWS | Text |
Details
biocViews | ATACSeq, CellBiology, ChIPSeq, Clustering, DifferentialExpression, FunctionalGenomics, GeneExpression, GeneRegulation, GraphAndNetwork, QualityControl, RNASeq, Regression, Sequencing, SingleCell, Software, Transcription, TranscriptomeVariant |
Version | 1.12.0 |
In Bioconductor since | BioC 3.13 (R-4.1) (3.5 years) |
License | GPL-2 |
Depends | R (>= 4.1) |
Imports | SingleCellExperiment, SummarizedExperiment, S4Vectors, scater, stats, smurf, apeglm(>= 1.13.3), emdbook, mclust, clue, dynamicTreeCut, matrixStats, dplyr, plyr, ggplot2, ComplexHeatmap, forestplot, RColorBrewer, rlang, lpSolve, grid, grDevices, graphics, utils, pbapply |
System Requirements | |
URL | https://github.com/Wancen/airpart |
Bug Reports | https://github.com/Wancen/airpart/issues |
See More
Suggests | knitr, rmarkdown, roxygen2 (>= 6.0.0), testthat (>= 3.0.0), gplots, tidyr |
Linking To | |
Enhances | |
Depends On Me | |
Imports Me | |
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Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
Source Package | airpart_1.12.0.tar.gz |
Windows Binary | airpart_1.12.0.zip |
macOS Binary (x86_64) | airpart_1.12.0.tgz |
macOS Binary (arm64) | airpart_1.12.0.tgz |
Source Repository | git clone https://git.bioconductor.org/packages/airpart |
Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/airpart |
Bioc Package Browser | https://code.bioconductor.org/browse/airpart/ |
Package Short Url | https://bioconductor.org/packages/airpart/ |
Package Downloads Report | Download Stats |