DOI: 10.18129/B9.bioc.Rhtslib  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see Rhtslib.

HTSlib high-throughput sequencing library as an R package

Bioconductor version: 3.16

This package provides version 1.15.1 of the 'HTSlib' C library for high-throughput sequence analysis. The package is primarily useful to developers of other R packages who wish to make use of HTSlib. Motivation and instructions for use of this package are in the vignette, vignette(package="Rhtslib", "Rhtslib").

Author: Nathaniel Hayden [led, aut], Martin Morgan [aut], Hervé Pagès [aut, cre]

Maintainer: Hervé Pagès <hpages.on.github at gmail.com>

Citation (from within R, enter citation("Rhtslib")):


To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



HTML R Script Motivation and use of Rhtslib
PDF   Reference Manual
Text   NEWS


biocViews DataImport, Sequencing, Software
Version 2.0.0
In Bioconductor since BioC 3.1 (R-3.2) (8 years)
License LGPL (>= 2)
Imports zlibbioc
LinkingTo zlibbioc
Suggests knitr, rmarkdown, BiocStyle
SystemRequirements libbz2 & liblzma & libcurl (with header files), GNU make
URL https://bioconductor.org/packages/Rhtslib http://www.htslib.org/
BugReports https://github.com/Bioconductor/Rhtslib/issues
Depends On Me
Imports Me deepSNV, diffHic, maftools, mitoClone2, scPipe
Suggests Me
Links To Me ArrayExpressHTS, bamsignals, BitSeq, csaw, deepSNV, DiffBind, diffHic, epialleleR, FLAMES, h5vc, maftools, methylKit, mitoClone2, podkat, qrqc, QuasR, Rfastp, Rsamtools, scPipe, seqbias, ShortRead, TransView, VariantAnnotation
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Rhtslib_2.0.0.tar.gz
Windows Binary Rhtslib_2.0.0.zip (64-bit only)
macOS Binary (x86_64) Rhtslib_2.0.0.tgz
macOS Binary (arm64) Rhtslib_2.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/Rhtslib
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/Rhtslib
Bioc Package Browser https://code.bioconductor.org/browse/Rhtslib/
Package Short Url https://bioconductor.org/packages/Rhtslib/
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: