Wrench normalization for sparse count data

Bioconductor version: Release (3.19)

Wrench is a package for normalization sparse genomic count data, like that arising from 16s metagenomic surveys.

Author: Senthil Kumar Muthiah [aut], Hector Corrada Bravo [aut, cre]

Maintainer: Hector Corrada Bravo <hcorrada at gmail.com>

Citation (from within R, enter citation("Wrench")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

Wrench HTML R Script
Reference Manual PDF


biocViews Normalization, Sequencing, Software
Version 1.22.0
In Bioconductor since BioC 3.8 (R-3.5) (5.5 years)
License Artistic-2.0
Depends R (>= 3.5.0)
Imports limma, matrixStats, locfit, stats, graphics
System Requirements
URL https://github.com/HCBravoLab/Wrench
Bug Reports https://github.com/HCBravoLab/Wrench/issues
See More
Suggests knitr, rmarkdown, metagenomeSeq, DESeq2, edgeR
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Imports Me metagenomeSeq
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Wrench_1.22.0.tar.gz
Windows Binary Wrench_1.22.0.zip
macOS Binary (x86_64) Wrench_1.22.0.tgz
macOS Binary (arm64) Wrench_1.22.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/Wrench
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/Wrench
Bioc Package Browser https://code.bioconductor.org/browse/Wrench/
Package Short Url https://bioconductor.org/packages/Wrench/
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