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This is the development version of ERSSA; for the stable release version, see ERSSA.

Empirical RNA-seq Sample Size Analysis

Bioconductor version: Development (3.19)

The ERSSA package takes user supplied RNA-seq differential expression dataset and calculates the number of differentially expressed genes at varying biological replicate levels. This allows the user to determine, without relying on any a priori assumptions, whether sufficient differential detection has been acheived with their RNA-seq dataset.

Author: Zixuan Shao [aut, cre]

Maintainer: Zixuan Shao <Zixuanshao.zach at>

Citation (from within R, enter citation("ERSSA")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


Reference Manual PDF


biocViews DifferentialExpression, GeneExpression, ImmunoOncology, MultipleComparison, QualityControl, RNASeq, Software, Transcription
Version 1.21.0
In Bioconductor since BioC 3.8 (R-3.5) (5.5 years)
License GPL-3 | file LICENSE
Depends R (>= 4.0.0)
Imports edgeR(>= 3.23.3), DESeq2(>= 1.21.16), ggplot2 (>= 3.0.0), RColorBrewer (>= 1.1-2), plyr (>= 1.8.4), BiocParallel(>= 1.15.8), apeglm(>= 1.4.2), grDevices, stats, utils
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