DOI: 10.18129/B9.bioc.DSS  

This is the development version of DSS; for the stable release version, see DSS.

Dispersion shrinkage for sequencing data

Bioconductor version: Development (3.18)

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Author: Hao Wu<hao.wu at emory.edu>, Hao Feng<hxf155 at case.edu>

Maintainer: Hao Wu <hao.wu at emory.edu>, Hao Feng <hxf155 at case.edu>

Citation (from within R, enter citation("DSS")):


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biocViews DNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software
Version 2.49.0
In Bioconductor since BioC 2.11 (R-2.15) (10.5 years)
License GPL
Depends R (>= 3.5.0), methods, Biobase, BiocParallel, bsseq, parallel
Imports utils, graphics, stats, splines
Suggests BiocStyle, knitr, rmarkdown
Depends On Me DeMixT
Imports Me borealis, DMRcate, kissDE, metaseqR2, methylSig
Suggests Me biscuiteer, methrix, NanoMethViz, PROPER
Links To Me
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Source Package
Windows Binary DSS_2.49.0.zip
macOS Binary (x86_64) DSS_2.49.0.tgz
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/DSS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DSS
Bioc Package Browser https://code.bioconductor.org/browse/DSS/
Package Short Url https://bioconductor.org/packages/DSS/
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