Welcome to the new bioconductor.org!


A statistical normalization method and differential expression analysis for RNA-seq data between different species

Bioconductor version: Release (3.18)

This package provides a scale based normalization (SCBN) method to identify genes with differential expression between different species. It takes into account the available knowledge of conserved orthologous genes and the hypothesis testing framework to detect differentially expressed orthologous genes. The method on this package are described in the article 'A statistical normalization method and differential expression analysis for RNA-seq data between different species' by Yan Zhou, Jiadi Zhu, Tiejun Tong, Junhui Wang, Bingqing Lin, Jun Zhang (2018, pending publication).

Author: Yan Zhou

Maintainer: Yan Zhou <2160090406 at email.szu.edu.cn>

Citation (from within R, enter citation("SCBN")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

SCBN Tutorial HTML R Script
Reference Manual PDF


biocViews DifferentialExpression, GeneExpression, Normalization, Software
Version 1.20.0
In Bioconductor since BioC 3.8 (R-3.5) (5.5 years)
License GPL-2
Depends R (>= 3.5.0)
Imports stats
System Requirements
See More
Suggests knitr, rmarkdown, BiocStyle, BiocManager
Linking To
Depends On Me
Imports Me TEKRABber
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package SCBN_1.20.0.tar.gz
Windows Binary SCBN_1.20.0.zip (64-bit only)
macOS Binary (x86_64) SCBN_1.20.0.tgz
macOS Binary (arm64) SCBN_1.20.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/SCBN
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/SCBN
Bioc Package Browser https://code.bioconductor.org/browse/SCBN/
Package Short Url https://bioconductor.org/packages/SCBN/
Package Downloads Report Download Stats