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BatchSVG

This is the development version of BatchSVG; to use it, please install the devel version of Bioconductor.

Identify Batch-Biased Features in Spatially Variable Genes


Bioconductor version: Development (3.21)

`BatchSVG` is a feature-based Quality Control (QC) to identify SVGs on spatial transcriptomics data with specific types of batch effect. Regarding to the spatial transcriptomics data experiments, the batch can be defined as "sample", "sex", and etc.The `BatchSVG` method is based on binomial deviance model (Townes et al, 2019) and applies cutoffs based on the number of standard deviation (nSD) of relative change in deviance and rank difference as the data-driven thresholding approach to detect the batch-biased outliers.

Author: Christine Hou [aut, cre] ORCID iD ORCID: 0009-0001-5350-0629 , Jacqui Thompson [aut], Stephanie C. Hicks [aut, fnd] ORCID iD ORCID: 0000-0002-7858-0231

Maintainer: Christine Hou <chris2018hou at gmail.com>

Citation (from within R, enter citation("BatchSVG")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("BatchSVG")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BatchSVG")
01 Tutorial for spe data object HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews BatchEffect, QualityControl, Software, Spatial, Transcriptomics
Version 0.99.9
In Bioconductor since BioC 3.21 (R-4.5)
License Artistic-2.0
Depends R (>= 4.5.0)
Imports scry, dplyr, stats, rlang, cowplot, ggrepel, ggplot2, RColorBrewer, scales, SummarizedExperiment
System Requirements
URL https://github.com/christinehou11/BatchSVG https://christinehou11.github.io/BatchSVG
Bug Reports https://github.com/christinehou11/BatchSVG/issues
See More
Suggests testthat (>= 3.0.0), knitr, rmarkdown, BiocStyle, spatialLIBD
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package BatchSVG_0.99.9.tar.gz
Windows Binary (x86_64) BatchSVG_0.99.9.zip
macOS Binary (x86_64) BatchSVG_0.99.9.tgz
macOS Binary (arm64) BatchSVG_0.99.9.tgz
Source Repository git clone https://git.bioconductor.org/packages/BatchSVG
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/BatchSVG
Bioc Package Browser https://code.bioconductor.org/browse/BatchSVG/
Package Short Url https://bioconductor.org/packages/BatchSVG/
Package Downloads Report Download Stats