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This is the development version of RUVnormalize; for the stable release version, see RUVnormalize.

RUV for normalization of expression array data

Bioconductor version: Development (3.19)

RUVnormalize is meant to remove unwanted variation from gene expression data when the factor of interest is not defined, e.g., to clean up a dataset for general use or to do any kind of unsupervised analysis.

Author: Laurent Jacob

Maintainer: Laurent Jacob <laurent.jacob at>

Citation (from within R, enter citation("RUVnormalize")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

RUVnormalize PDF R Script
Reference Manual PDF


biocViews Normalization, Software, StatisticalMethod
Version 1.37.0
In Bioconductor since BioC 3.0 (R-3.1) (9.5 years)
License GPL-3
Depends R (>= 2.10.0)
Imports RUVnormalizeData, Biobase
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Follow Installation instructions to use this package in your R session.

Source Package RUVnormalize_1.37.0.tar.gz
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macOS Binary (x86_64) RUVnormalize_1.37.0.tgz
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Source Repository (Developer Access) git clone
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