STAN

DOI: 10.18129/B9.bioc.STAN    

The Genomic STate ANnotation Package

Bioconductor version: Release (3.13)

Genome segmentation with hidden Markov models has become a useful tool to annotate genomic elements, such as promoters and enhancers. STAN (genomic STate ANnotation) implements (bidirectional) hidden Markov models (HMMs) using a variety of different probability distributions, which can model a wide range of current genomic data (e.g. continuous, discrete, binary). STAN de novo learns and annotates the genome into a given number of 'genomic states'. The 'genomic states' may for instance reflect distinct genome-associated protein complexes (e.g. 'transcription states') or describe recurring patterns of chromatin features (referred to as 'chromatin states'). Unlike other tools, STAN also allows for the integration of strand-specific (e.g. RNA) and non-strand-specific data (e.g. ChIP).

Author: Benedikt Zacher, Julia Ertl, Rafael Campos-Martin, Julien Gagneur, Achim Tresch

Maintainer: Rafael Campos-Martin <campos at mpipz.mpg.de>

Citation (from within R, enter citation("STAN")):

Installation

To install this package, start R (version "4.1") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("STAN")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("STAN")

 

PDF R Script The genomic STate ANnotation package
PDF   Reference Manual

Details

biocViews ChIPSeq, ChipOnChip, GenomeAnnotation, HiddenMarkovModel, ImmunoOncology, Microarray, RNASeq, Sequencing, Software, Transcription
Version 2.20.0
In Bioconductor since BioC 3.0 (R-3.1) (7 years)
License GPL (>= 2)
Depends methods, poilog, parallel
Imports GenomicRanges, IRanges, S4Vectors, BiocGenerics, GenomeInfoDb, Gviz, Rsolnp
LinkingTo
Suggests BiocStyle, gplots, knitr
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package STAN_2.20.0.tar.gz
Windows Binary STAN_2.20.0.zip
macOS 10.13 (High Sierra) STAN_2.20.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/STAN
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/STAN
Package Short Url https://bioconductor.org/packages/STAN/
Package Downloads Report Download Stats

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