InterCellar is a Bioconductor package that provides
an interactive Shiny application to enable the analysis of cell-cell communication from
single-cell RNA sequencing (scRNA-seq) data. Every step of the analysis can be
performed interactively, thus not requiring any programming skills. Moreover,
InterCellar runs on your local machine, avoiding issues related to data privacy.
InterCellar is distributed as a Bioconductor package and requires R (version “4.1”) and Bioconductor (version “3.13”).
InterCellar package enter:
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("InterCellar")
Once InterCellar is successfully installed, it can be loaded as follow:
In order to start the app, please run the following command:
InterCellar::run_app( reproducible = TRUE )
InterCellar should be opening in a browser. If this does not happen automatically,
please open a browser and navigate to the address shown (for example,
Listening on http://127.0.0.1:6134). The flag
reproducible = TRUE ensures that your results will
be reproducible across R sessions.
The following figure represents
InterCellar analysis workflow. We could not miss the opportunity
of depicting it as an interstellar journey.