DOI: 10.18129/B9.bioc.debCAM  

Deconvolution by Convex Analysis of Mixtures

Bioconductor version: Release (3.17)

An R package for fully unsupervised deconvolution of complex tissues. It provides basic functions to perform unsupervised deconvolution on mixture expression profiles by Convex Analysis of Mixtures (CAM) and some auxiliary functions to help understand the subpopulation-specific results. It also implements functions to perform supervised deconvolution based on prior knowledge of molecular markers, S matrix or A matrix. Combining molecular markers from CAM and from prior knowledge can achieve semi-supervised deconvolution of mixtures.

Author: Lulu Chen <luluchen at>

Maintainer: Lulu Chen <luluchen at>

Citation (from within R, enter citation("debCAM")):


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biocViews CellBiology, GeneExpression, Software
Version 1.18.0
In Bioconductor since BioC 3.10 (R-3.6) (4 years)
License GPL-2
Depends R (>= 3.5)
Imports methods, rJava, BiocParallel, stats, Biobase, SummarizedExperiment, corpcor, geometry, NMF, nnls, DMwR2, pcaPP, apcluster, graphics
Suggests knitr, rmarkdown, BiocStyle, testthat, GEOquery, rgl
SystemRequirements Java (>= 1.8)
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Source Package debCAM_1.18.0.tar.gz
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macOS Binary (arm64) debCAM_1.18.0.tgz
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