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Mass Spectrometry Backend for Reading Thermo Fisher Scientific raw Files

Bioconductor version: Release (3.19)

implements a MsBackend for the Spectra package using Thermo Fisher Scientific's NewRawFileReader .Net libraries. The package is generalizing the functionality introduced by the rawrr package Methods defined in this package are supposed to extend the Spectra Bioconductor package.

Author: Christian Panse [aut, cre] , Tobias Kockmann [aut] , Roger Gine Bertomeu [ctb]

Maintainer: Christian Panse <cp at>

Citation (from within R, enter citation("MsBackendRawFileReader")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

On Using and Extending the `MsBackendRawFileReader` Backend. HTML R Script
Reference Manual PDF


biocViews MassSpectrometry, Metabolomics, Proteomics, Software
Version 1.10.0
In Bioconductor since BioC 3.14 (R-4.1) (2.5 years)
License GPL-3
Depends R (>= 4.1), methods, Spectra(>= 1.5.8)
Imports ProtGenerics(>= 1.35.3), MsCoreUtils, S4Vectors, IRanges, rawrr(>= 1.10.1), utils, BiocParallel
System Requirements mono-runtime 4.x or higher (including System.Data library) on Linux/macOS, .Net Framework (>= 4.5.1) on Microsoft Windows.
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Suggests BiocStyle(>= 2.5), ExperimentHub, MsBackendMgf, knitr, lattice, mzR, protViz (>= 0.7), rmarkdown, tartare(>= 1.5), testthat
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Follow Installation instructions to use this package in your R session.

Source Package MsBackendRawFileReader_1.10.0.tar.gz
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macOS Binary (x86_64) MsBackendRawFileReader_1.10.0.tgz
macOS Binary (arm64) MsBackendRawFileReader_1.10.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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