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Differential Enrichment Scan 2

Bioconductor version: Release (3.19)

Integrated peak and differential caller, specifically designed for broad epigenomic signals.

Author: Dario Righelli [aut, cre], John Koberstein [aut], Bruce Gomes [aut], Nancy Zhang [aut], Claudia Angelini [aut], Lucia Peixoto [aut], Davide Risso [aut]

Maintainer: Dario Righelli <dario.righelli at>

Citation (from within R, enter citation("DEScan2")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:

DEScan2 Vignette HTML R Script
Reference Manual PDF


biocViews Coverage, Epigenetics, ImmunoOncology, PeakDetection, Sequencing, Software
Version 1.24.0
In Bioconductor since BioC 3.7 (R-3.5) (6 years)
License Artistic-2.0
Depends R (>= 3.5), GenomicRanges
Imports BiocParallel, BiocGenerics, ChIPpeakAnno, data.table, DelayedArray, GenomeInfoDb, GenomicAlignments, glue, IRanges, plyr, Rcpp (>= 0.12.13), rtracklayer, S4Vectors(>= 0.23.19), SummarizedExperiment, tools, utils
System Requirements
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Suggests BiocStyle, knitr, rmarkdown, testthat, edgeR, limma, EDASeq, RUVSeq, RColorBrewer, statmod
Linking To Rcpp, RcppArmadillo
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Follow Installation instructions to use this package in your R session.

Source Package DEScan2_1.24.0.tar.gz
Windows Binary
macOS Binary (x86_64) DEScan2_1.24.0.tgz
macOS Binary (arm64) DEScan2_1.24.0.tgz
Source Repository git clone
Source Repository (Developer Access) git clone
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