Changes in version 1.3.3 (2020-11-18) + Defunct function df_estimate() Changes in version 1.2.1 (2020-11-17) + pFdr adapted according to (Phipson and Smyth 2010) Changes in version 1.1.1 (2020-09-23) + Function contrastModel() added to support contrast rotation + Vignette extended + Deprecate function df_estimate() Changes in version 0.99.12 (2020-04-25) + Submitted to Bioconductor