Changes in version 2.0.0 MAJOR UPDATE Adding the Following Functionality: - Format, Library, and Testing Improvements o Enable processing of libraries with 1:many reagent:target assignments o Standardization and clarification of Annotation objects and symbol/identifier relationships o Implementation of factored quantile normalization for timecourse screens o Introduction of the simpleResult format and integration with associated functions o Conditional testing framework for quantifying and visualizing signal agreement between contrasts - Transition to gene set enrichment testing via Sparrow o Implement wrappers and provide recommendations fopr geneset enrichment testing in pooled screens o Implementation of GREAT-style pathway mapping for libraries with heterogenous target:gene mappings o Summarization tools for comparing enrichment signals across screens - New Visualization and Interpretation Tools o Signal Summary Barchart (Single or Multiple Contrasts) o Waterfall reagent/target/pathway visualization (Single Contrast) o Contrast comparison plots: - Concordance at the Top (CAT) - Probability Space scatter plots - UpSet plots with conditional overlap framework Changes in version 1.20.0 Inclusion of factored quantile normalization and additional convenience functions, typo revisions in the vignettes. Suppression of results dataframe reordering by ct.generateResults(). Implementation of alternative reagent:target assignment, useful for situations where reagents are known to target multiple valid targets. Changes in version 1.15.0 Various code updates, new functions added for visualization, compatibility with modern R objects. Russell Bainer redesignated as official maintainer. Changes in version 1.1.0 Miscellaneous minor report edits and performance upgrades. Bugfix to P-value based scoring algorithm. Peter Haverty designated as official maintainer. Changes in version 1.0.0 First official release to Bioconductor. Changes in version 0.99.0 Initial bioconductor submission.