edge 2.1.1: - Moderated F-test has been added for likelihood ratio test - Weights can be inputted into odp/lrt which allows it to work for RNA-Seq experiments with low samples - added function apply_jackstraw - fixed bug in build_study edge 2.0.0: The edge package was first released in 2005 and described in the publication: Jeffrey T. Leek, Eva Monsen, Alan R. Dabney, and John D. Storey. Edge: extraction and analysis of differential gene expression. Bioinformatics, 22(4):507–508, 2006. http://bioinformatics.oxfordjournals.org/content/22/4/507.abstract It was an independently released R package by the John Storey Lab, which included multi-threading and a graphical user interface. However, edge has been updated and will now be made available through Bioconductor; edge >=2.0.0 is the new version released through Bioconductor.