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This package is deprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

This is the development version of RefPlus; for the stable release version, see RefPlus.

A function set for the Extrapolation Strategy (RMA+) and Extrapolation Averaging (RMA++) methods.

Bioconductor version: Development (3.19)

The package contains functions for pre-processing Affymetrix data using the RMA+ and the RMA++ methods.

Author: Kai-Ming Chang <kaiming at gmail.com>, Chris Harbron <Chris.Harbron at astrazeneca.com>, Marie C South <Marie.C.South at astrazeneca.com>

Maintainer: Kai-Ming Chang <kaiming at gmail.com>

Citation (from within R, enter citation("RefPlus")):


To install this package, start R (version "4.4") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


Reference Manual PDF


biocViews Microarray, OneChannel, Preprocessing, Software
Version 1.73.1
In Bioconductor since BioC 2.0 (R-2.5) (17 years)
License GPL (>= 2)
Depends R (>= 2.8.0), Biobase(>= 2.1.0), affy(>= 1.20.0), affyPLM(>= 1.18.0), preprocessCore(>= 1.4.0)
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Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary RefPlus_1.73.1.zip (64-bit only)
macOS Binary (x86_64) RefPlus_1.73.1.tgz
macOS Binary (arm64) RefPlus_1.73.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/RefPlus
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RefPlus
Package Short Url https://bioconductor.org/packages/RefPlus/
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