synergyfinder

DOI: 10.18129/B9.bioc.synergyfinder    

This package is for version 3.8 of Bioconductor; for the stable, up-to-date release version, see synergyfinder.

Calculate and Visualize Synergy Scores for Drug Combinations

Bioconductor version: 3.8

Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.

Author: Liye He <liye.he at helsinki.fi>, Jing Tang <jing.tang at helsinki.fi>

Maintainer: Liye He <liye.he at helsinki.fi>

Installation

To install this package, start R (version "3.5") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("synergyfinder")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("synergyfinder")

 

PDF	R Script	synergyfinder
PDF		Reference Manual
Text		NEWS
Text		LICENSE

Details

biocViews	Software, Statistical Method
Version	1.8.0
In Bioconductor since	BioC 3.4 (R-3.3) (2.5 years)
License	Mozilla Public License 2.0 + file LICENSE
Depends
Imports	drc (>= 2.5-12), reshape2 (>= 1.4.1), SpatialExtremes (>= 2.0-2), ggplot2 (>= 2.1.0), gridBase (>= 0.4-7), grid (>= 3.2.4), lattice (>= 0.20-33), gplots (>= 3.0.0), nleqslv (>= 3.0), stats (>= 3.3.0), graphics (>= 3.3.0), grDevices (>= 3.3.0)
LinkingTo
Suggests	knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	synergyfinder_1.8.0.tar.gz
Windows Binary	synergyfinder_1.8.0.zip
Mac OS X 10.11 (El Capitan)	synergyfinder_1.8.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/synergyfinder
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/synergyfinder
Package Short Url	http://bioconductor.org/packages/synergyfinder/
Package Downloads Report	Download Stats