mbrPreprocess,matrix-method {RTNduals}R Documentation

A preprocessing function for objects of class MBR.

Description

A preprocessing function for objects of class MBR.

Usage

## S4 method for signature 'matrix'
mbrPreprocess(gexp, regulatoryElements,
  verbose = TRUE, ...)

Arguments

gexp

A numerical matrix, typically with mRNA and/or miRNA expression values.

regulatoryElements

A named vector with regulatory elements listed in 'gexp' rownames.

verbose

A single logical value specifying to display detailed messages (when verbose=TRUE) or not (when verbose=FALSE).

...

Additional arguments passed on to tni.preprocess function.

Value

A preprocessed 'MBR-class' object.

Examples

##--- load a dataset for demonstration
data("dt4rtn", package = "RTN")
gexp <- dt4rtn$gexp
annot <- dt4rtn$gexpIDs
tfs <- dt4rtn$tfs[c("IRF8","IRF1","PRDM1","AFF3","E2F3")]

##--- run mbrPreprocess
rmbr <- mbrPreprocess(gexp=gexp, regulatoryElements = tfs,
rowAnnotation=annot)


[Package RTNduals version 1.4.4 Index]