DOI: 10.18129/B9.bioc.sSNAPPY  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see sSNAPPY.

Single Sample directioNAl Pathway Perturbation analYsis

Bioconductor version: 3.16

A single sample pathway perturbation testing method for RNA-seq data. The method propagates changes in gene expression down gene-set topologies to compute single-sample directional pathway perturbation scores that reflect potential directions of changes.Perturbation scores can be used to test significance of pathway perturbation at both individual-sample and treatment levels.

Author: Wenjun Liu [aut, cre]

Maintainer: Wenjun Liu <wenjun.liu at>

Citation (from within R, enter citation("sSNAPPY")):


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biocViews GeneExpression, GeneSetEnrichment, GeneSignaling, Software
Version 1.2.5
In Bioconductor since BioC 3.15 (R-4.2) (1 year)
License GPL-3
Depends R (>= 4.2.0)
Imports dplyr, magrittr, rlang, stats, purrr, BiocParallel, graphite, Rcpp, tibble, ggplot2, ggraph, igraph, reshape2,, SummarizedExperiment, edgeR, methods, ggforce, ggnewscale, pheatmap, utils
LinkingTo Rcpp, RcppArmadillo
Suggests BiocManager, BiocStyle, cowplot, DT, htmltools, knitr, pander, rmarkdown, spelling, stringr, testthat (>= 3.0.0), tidyverse
SystemRequirements C++11
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