DOI: 10.18129/B9.bioc.metapone  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see metapone.

Conducts pathway test of metabolomics data using a weighted permutation test

Bioconductor version: 3.16

The package conducts pathway testing from untargetted metabolomics data. It requires the user to supply feature-level test results, from case-control testing, regression, or other suitable feature-level tests for the study design. Weights are given to metabolic features based on how many metabolites they could potentially match to. The package can combine positive and negative mode results in pathway tests.

Author: Leqi Tian [aut], Tianwei Yu [aut], Tianwei Yu [cre]

Maintainer: Tianwei Yu <yutianwei at>

Citation (from within R, enter citation("metapone")):


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biocViews MassSpectrometry, Metabolomics, Pathways, Software, Technology
Version 1.4.0
In Bioconductor since BioC 3.14 (R-4.1) (1.5 years)
License Artistic-2.0
Depends R (>= 4.1.0), BiocParallel, fields, markdown, fdrtool, fgsea, ggplot2, ggrepel
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