DOI: 10.18129/B9.bioc.metagene2  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see metagene2.

A package to produce metagene plots

Bioconductor version: 3.16

This package produces metagene plots to compare coverages of sequencing experiments at selected groups of genomic regions. It can be used for such analyses as assessing the binding of DNA-interacting proteins at promoter regions or surveying antisense transcription over the length of a gene. The metagene2 package can manage all aspects of the analysis, from normalization of coverages to plot facetting according to experimental metadata. Bootstraping analysis is used to provide confidence intervals of per-sample mean coverages.

Author: Eric Fournier [cre, aut], Charles Joly Beauparlant [aut], Cedric Lippens [aut], Arnaud Droit [aut]

Maintainer: Eric Fournier <ericfournier2 at>

Citation (from within R, enter citation("metagene2")):


To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))


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biocViews Alignment, ChIPSeq, Coverage, Genetics, MultipleComparison, Sequencing, Software
Version 1.14.0
In Bioconductor since BioC 3.9 (R-3.6) (4 years)
License Artistic-2.0
Depends R (>= 4.0), R6 (>= 2.0), GenomicRanges, BiocParallel
Imports rtracklayer, tools, GenomicAlignments, GenomeInfoDb, IRanges, ggplot2, Rsamtools, purrr, data.table, methods, dplyr, magrittr, reshape2
Suggests BiocGenerics, RUnit, knitr, BiocStyle, rmarkdown
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