DOI: 10.18129/B9.bioc.gespeR  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see gespeR.

Gene-Specific Phenotype EstimatoR

Bioconductor version: 3.16

Estimates gene-specific phenotypes from off-target confounded RNAi screens. The phenotype of each siRNA is modeled based on on-targeted and off-targeted genes, using a regularized linear regression model.

Author: Fabian Schmich

Maintainer: Fabian Schmich <fabian.schmich at>

Citation (from within R, enter citation("gespeR")):


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PDF R Script An R package for deconvoluting off-target confounded RNAi screens
PDF   Reference Manual


biocViews CellBasedAssays, GeneTarget, ImmunoOncology, Preprocessing, Regression, Software, Visualization
Version 1.30.0
In Bioconductor since BioC 3.1 (R-3.2) (8 years)
License GPL-3
Depends methods, graphics, ggplot2, R (>= 2.10)
Imports Matrix, glmnet, cellHTS2, Biobase, biomaRt, doParallel, parallel, foreach, reshape2, dplyr
Suggests knitr
Depends On Me
Imports Me
Suggests Me
Links To Me
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