DOI: 10.18129/B9.bioc.TargetScore  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see TargetScore.

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

Bioconductor version: 3.16

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at>

Citation (from within R, enter citation("TargetScore")):


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biocViews Software, miRNA
Version 1.36.0
In Bioconductor since BioC 2.13 (R-3.0) (9.5 years)
License GPL-2
Depends pracma, Matrix
Suggests TargetScoreData, gplots, Biobase, GEOquery
Depends On Me
Imports Me
Suggests Me TargetScoreData
Links To Me
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