DOI: 10.18129/B9.bioc.ReactomeGraph4R  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see ReactomeGraph4R.

Interface for the Reactome Graph Database

Bioconductor version: 3.16

Pathways, reactions, and biological entities in Reactome knowledge are systematically represented as an ordered network. Instances are represented as nodes and relationships between instances as edges; they are all stored in the Reactome Graph Database. This package serves as an interface to query the interconnected data from a local Neo4j database, with the aim of minimizing the usage of Neo4j Cypher queries.

Author: Chi-Lam Poon [aut, cre] , Reactome [cph]

Maintainer: Chi-Lam Poon <clpoon807 at>

Citation (from within R, enter citation("ReactomeGraph4R")):


To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))


For older versions of R, please refer to the appropriate Bioconductor release.


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biocViews DataImport, GraphAndNetwork, Network, Pathways, Reactome, Software
Version 1.6.0
In Bioconductor since BioC 3.13 (R-4.1) (2 years)
License Apache License (>= 2)
Depends R (>= 4.1)
Imports neo4r, utils, getPass, jsonlite, purrr, magrittr, data.table, rlang, ReactomeContentService4R, doParallel, parallel, foreach
Suggests knitr, rmarkdown, testthat, stringr, networkD3, visNetwork, wesanderson
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