DOI: 10.18129/B9.bioc.LOLA  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see LOLA.

Locus overlap analysis for enrichment of genomic ranges

Bioconductor version: 3.16

Provides functions for testing overlap of sets of genomic regions with public and custom region set (genomic ranges) databases. This makes it possible to do automated enrichment analysis for genomic region sets, thus facilitating interpretation of functional genomics and epigenomics data.

Author: Nathan Sheffield <> [aut, cre], Christoph Bock [ctb]

Maintainer: Nathan Sheffield <nathan at>

Citation (from within R, enter citation("LOLA")):


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HTML R Script 1. Getting Started with LOLA
HTML R Script 2. Using LOLA Core
HTML R Script 3. Choosing a Universe
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Text   NEWS


biocViews ChIPSeq, FunctionalGenomics, GeneRegulation, GeneSetEnrichment, GenomeAnnotation, MethylSeq, Sequencing, Software, SystemsBiology
Version 1.28.0
In Bioconductor since BioC 3.2 (R-3.2) (7.5 years)
License GPL-3
Depends R (>= 3.5.0)
Imports BiocGenerics, S4Vectors, IRanges, GenomicRanges, data.table, reshape2, utils, stats, methods
Suggests parallel, testthat, knitr, BiocStyle, rmarkdown
Enhances simpleCache, qvalue, ggplot2
Depends On Me
Imports Me
Suggests Me COCOA, DeepBlueR, MAGAR, MIRA, ramr
Links To Me
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