DOI: 10.18129/B9.bioc.DominoEffect  

This package is for version 3.16 of Bioconductor; for the stable, up-to-date release version, see DominoEffect.

Identification and Annotation of Protein Hotspot Residues

Bioconductor version: 3.16

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Author: Marija Buljan and Peter Blattmann

Maintainer: Marija Buljan <marija.buljan.2 at>, Peter Blattmann <blattmann at>

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biocViews Alignment, Proteomics, SequenceMatching, Software, SomaticMutation
Version 1.18.0
In Bioconductor since BioC 3.7 (R-3.5) (5 years)
License GPL (>= 3)
Depends R (>= 3.5)
Imports biomaRt, data.table, utils, stats, Biostrings, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods
Suggests knitr, testthat, rmarkdown
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