scRepertoire

DOI: 10.18129/B9.bioc.scRepertoire    

A toolkit for single-cell immune receptor profiling

Bioconductor version: Release (3.15)

scRepertoire was built to process data derived from the 10x Genomics Chromium Immune Profiling for both T-cell receptor (TCR) and immunoglobulin (Ig) enrichment workflows and subsequently interacts with the popular Seurat and SingleCellExperiment R packages. It also allows for general analysis of single-cell clonotype information without the use of expression information. The package functions as a wrapper for Startrac and powerTCR R packages.

Author: Nick Borcherding [aut, cre]

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("scRepertoire")):

Installation

To install this package, start R (version "4.2") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("scRepertoire")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("scRepertoire")

 

HTML R Script Using scRepertoire
PDF   Reference Manual
Text   NEWS

Details

biocViews Annotation, Classification, ImmunoOncology, Sequencing, SingleCell, Software
Version 1.6.0
In Bioconductor since BioC 3.12 (R-4.0) (2 years)
License Apache License 2.0
Depends ggplot2, R (>= 4.0)
Imports stringdist, dplyr, reshape2, ggalluvial, stringr, vegan, powerTCR, SummarizedExperiment, plyr, parallel, doParallel, methods, utils, rlang, igraph, SeuratObject
LinkingTo
Suggests knitr, rmarkdown, BiocStyle, scater, circlize, scales, Seurat
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package scRepertoire_1.6.0.tar.gz
Windows Binary scRepertoire_1.6.0.zip
macOS Binary (x86_64) scRepertoire_1.6.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/scRepertoire
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/scRepertoire
Package Short Url https://bioconductor.org/packages/scRepertoire/
Package Downloads Report Download Stats

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