normalizeMethylation.quantile {lumi} | R Documentation |
Quantile normalization of Illumina Infinium methylation data at probe level. Input data is a MethyLumiM object
normalizeMethylation.quantile(methyLumiM, separateColor = FALSE, reference = NULL, ...)
methyLumiM |
a MethyLumiM object includes Illumina Infinium methylation data |
separateColor |
determine whether separately normalize two color channels |
reference |
the reference vector (same length as the number of matrix rows) for quanitle normalization |
... |
other parameters used by normalize.quantiles.robust method |
Return an object (same class as input methyLumiM) with updated "methylated" and "unmethylated" data matrix after background level adjustment.
Pan DU
See Also lumiMethyN
, and normalizeMethylation.ssn
data(example.lumiMethy) lumiMethy.norm = normalizeMethylation.quantile(example.lumiMethy)