fudge2 {siggenes} | R Documentation |
Computes the fudge factor as described by Tusher et al. (2001).
fudge2(r, s, alpha = seq(0, 1, 0.05), include.zero = TRUE)
r |
a numeric vector. The numerator of the test statistic computed for each gene is represented by one component of this vector. |
s |
a numeric vector. Each component of this vector corresponds to the denominator of the test statistic of a gene. |
alpha |
a numeric value or vector specifying quantiles of the
|
include.zero |
if |
s.zero |
the value of the fudge factor s0. |
alpha.hat |
the optimal quantile of the |
vec.cv |
the vector of the coefficients of variations.
Following Tusher et al. (2001), the optimal |
msg |
a character string summarizing the most important information about the fudge factor. |
Holger Schwender, holger.schw@gmx.de
Tusher, V., Tibshirani, R., and Chu, G. (2001). Significance Analysis of Microarrays Applied to the Ionizing Radiation Response. PNAS, 98, 5116-5121.