ssea.analyze.statistic {Mergeomics} | R Documentation |
ssea.analyze.statistic
estimates the enrichment score based
on observed and expected ones.
ssea.analyze.statistic(o, e)
o |
observed enrichment score |
e |
expected enrichment score |
score |
estimated enrichment score based on observed and expected scores |
Ville-Petteri Makinen
Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Makinen V-P, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. BMC genomics. 2016;17(1):874.
## O and E the observed and expected counts of positive findings ## (enrichment scores) at a given cutoff: set.seed(1) o <- rnorm(1) e <- rnorm(1) ## find the final enrichment score from the observed and estimated scores: z <- ssea.analyze.statistic(o, e)