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source("https://bioconductor.org/biocLite.R")
biocLite("trio")

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trio

 

Testing of SNPs and SNP Interactions in Case-Parent Trio Studies

Bioconductor version: Release (3.1)

Testing SNPs and SNP interactions with a genotypic TDT. This package furthermore contains functions for computing pairwise values of LD measures and for identifying LD blocks, as well as functions for setting up matched case pseudo-control genotype data for case-parent trios in order to run trio logic regression, for imputing missing genotypes in trios, for simulating case-parent trios with disease risk dependent on SNP interaction, and for power and sample size calculation in trio data.

Author: Holger Schwender, Qing Li, Philipp Berger, Christoph Neumann, Margaret Taub, Ingo Ruczinski

Maintainer: Holger Schwender <holger.schw at gmx.de>

Citation (from within R, enter citation("trio")):

Installation

To install this package, start R and enter:

## try http if https is not available
source("https://bioconductor.org/biocLite.R")
biocLite("trio")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("trio")

 

PDF R Script Trio Logic Regression and genotypic TDT
PDF   Reference Manual

Details

biocViews GeneticVariability, Genetics, Microarray, SNP, Software
Version 3.6.0
In Bioconductor since BioC 2.13 (R-3.0) (2 years)
License LGPL-2
Depends R (>= 3.0.1)
Imports
LinkingTo
Suggests survival, haplo.stats, mcbiopi, siggenes, splines, LogicReg (>= 1.5.3), logicFS(>= 1.28.1), KernSmooth, VariantAnnotation
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source trio_3.6.0.tar.gz
Windows Binary trio_3.6.0.zip
Mac OS X 10.6 (Snow Leopard) trio_3.6.0.tgz
Mac OS X 10.9 (Mavericks) trio_3.6.0.tgz
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/trio/tree/release-3.1
Package Short Url http://bioconductor.org/packages/trio/
Package Downloads Report Download Stats

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