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Simulation of cancer progresion with order restrictions

Bioconductor version: 3.0

Functions for simulating and plotting cancer progression data, including drivers and passengers, and allowing for order restrictions. Simulations use continuous-time models (based on Bozic et al., 2010 and McFarland et al., 2013) and fitness functions account for possible restrictions in the order of accumulation of mutations.

Author: Ramon Diaz-Uriarte.

Maintainer: Ramon Diaz-Uriarte <rdiaz02 at>

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PDF R Script OncoSimulR Overview
PDF   Reference Manual
Text   NEWS


biocViews BiologicalQuestion, Software, SomaticMutation
Version 1.0.0
In Bioconductor since BioC 3.0 (R-3.1)
License GPL (>= 3)
Depends R (>= 3.1.0)
Imports Rcpp (>= 0.11.1), parallel, data.table, graph, Rgraphviz
LinkingTo Rcpp
Suggests BiocStyle, knitr, Oncotree
SystemRequirements C++11
Depends On Me
Imports Me
Suggests Me
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