Types of Binary Relations

Type Description Sample BioPAX Structure Inferred Binary Relation(s)
controls-state-change-of First protein controls a reaction that changes the state of the second protein.
controls-transport-of First protein controls a reaction that changes the cellular location of the second protein.
controls-phosphorylation-of First protein controls a reaction that changes the phosphorylation status of the second protein.
controls-expression-of First protein controls a conversion or a template reaction that changes expression of the second protein.
catalysis-precedes First protein controls a reaction whose output molecule is input to another reaction controled by the second protein.
in-complex-with Proteins are members of the same complex.
interacts-with Proteins are participants of the same MolecularInteraction.
neighbor-of Proteins are participants or controlers of the same interaction.
consumption-controled-by The small molecule is consumed by a reaction that is controled by a protein
controls-production-of The protein controls a reaction of which the small molecule is an output.
controls-transport-of-chemical The protein controls a reaction that changes cellular location of the small molecule.
chemical-affects A small molecule has an effect on the protein state.
reacts-with Small molecules are input to a biochemical reaction.
used-to-produce A reaction consumes a small molecule to produce another small molecule.
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