hopach

Hierarchical Ordered Partitioning and Collapsing Hybrid (HOPACH)

Bioconductor version: 2.6

The HOPACH clustering algorithm builds a hierarchical tree of clusters by recursively partitioning a data set, while ordering and possibly collapsing clusters at each level. The algorithm uses the Mean/Median Split Silhouette (MSS) criteria to identify the level of the tree with maximally homogeneous clusters. It also runs the tree down to produce a final ordered list of the elements. The non-parametric bootstrap allows one to estimate the probability that each element belongs to each cluster (fuzzy clustering).

Author: Katherine S. Pollard, with Mark J. van der Laan <laan at stat.berkeley.edu> and Greg Wall

Maintainer: Katherine S. Pollard <katherine.pollard at gladstone.ucsf.edu>

To install this package, start R and enter:

    source("http://bioconductor.org/biocLite.R")
    biocLite("hopach")

To cite this package in a publication, start R and enter:

    citation("hopach")

Documentation

PDF bootplot.pdf
PDF dplot.pdf
PDF R Script hopach
PDF hopachManuscript.pdf
PDF MSS.pdf
PDF   Reference Manual

Details

biocViews Clustering
Depends R (>= 2.6.0), cluster, Biobase, methods
Imports
Suggests
System Requirements
License GPL (>= 2)
URL http://www.stat.berkeley.edu/~laan/, http://docpollard.com/
Depends On Me
Imports Me
Suggests Me BiocCaseStudies
Version 2.8.0
Since Bioconductor 1.6 (R-2.1) or earlier

Package Downloads

Package Source hopach_2.8.0.tar.gz
Windows Binary hopach_2.8.0.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary hopach_2.8.0.tgz
Package Downloads Report Download Stats

Workflows »

Common Bioconductor workflows include:

 

Mailing Lists »

Post questions about Bioconductor packages to our mailing lists. Read the posting guide before posting!

Fred Hutchinson Cancer Research Center