##############################################################################
##############################################################################
###
### Running command:
###
###   F:\biocbuild\bbs-3.15-bioc\R\bin\R.exe CMD check --no-multiarch --install=check:Repitools.install-out.txt --library=F:\biocbuild\bbs-3.15-bioc\R\library --no-vignettes --timings Repitools_1.42.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory 'F:/biocbuild/bbs-3.15-bioc/meat/Repitools.Rcheck'
* using R version 4.2.1 (2022-06-23 ucrt)
* using platform: x86_64-w64-mingw32 (64-bit)
* using session charset: UTF-8
* using option '--no-vignettes'
* checking for file 'Repitools/DESCRIPTION' ... OK
* this is package 'Repitools' version '1.42.0'
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking whether package 'Repitools' can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking 'build' directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of 'data' directory ... OK
* checking data for non-ASCII characters ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking line endings in C/C++/Fortran sources/headers ... OK
* checking line endings in Makefiles ... OK
* checking compilation flags in Makevars ... OK
* checking for GNU extensions in Makefiles ... OK
* checking for portable use of $(BLAS_LIBS) and $(LAPACK_LIBS) ... OK
* checking use of PKG_*FLAGS in Makefiles ... OK
* checking compiled code ... OK
* checking sizes of PDF files under 'inst/doc' ... OK
* checking files in 'vignettes' ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                   user system elapsed
methylEst         56.74   2.40   59.21
empBayes          29.67   2.17   31.84
cpgDensityCalc     9.01   0.64  142.83
sequenceCalc       7.95   0.31    8.27
BayMethList-class  7.63   0.37    8.05
determineOffset    4.78   0.30    5.08
* checking for unstated dependencies in 'tests' ... OK
* checking tests ...
  Running 'tests.R'
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in 'inst/doc' ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: OK

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###
### Running command:
###
###   F:\biocbuild\bbs-3.15-bioc\R\bin\R.exe CMD INSTALL Repitools
###
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* installing to library 'F:/biocbuild/bbs-3.15-bioc/R/library'
* installing *source* package 'Repitools' ...
** using staged installation
** libs
gcc  -I"F:/biocbuild/bbs-3.15-bioc/R/include" -DNDEBUG     -I"C:/rtools42/x86_64-w64-mingw32.static.posix/include"  -D R_NO_REMAP -I.    -O2 -Wall  -std=gnu99 -mfpmath=sse -msse2 -mstackrealign  -c const.c -o const.o
gcc  -I"F:/biocbuild/bbs-3.15-bioc/R/include" -DNDEBUG     -I"C:/rtools42/x86_64-w64-mingw32.static.posix/include"  -D R_NO_REMAP -I.    -O2 -Wall  -std=gnu99 -mfpmath=sse -msse2 -mstackrealign  -c hyp2f1.c -o hyp2f1.o
In file included from hyp2f1.c:81:
./mconf.h:100: warning: "DOMAIN" redefined
  100 | #define DOMAIN  1 /* argument domain error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:29: note: this is the location of the previous definition
   29 | #define DOMAIN  _DOMAIN
      | 
In file included from hyp2f1.c:81:
./mconf.h:101: warning: "SING" redefined
  101 | #define SING  2 /* argument singularity */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:30: note: this is the location of the previous definition
   30 | #define SING  _SING
      | 
In file included from hyp2f1.c:81:
./mconf.h:102: warning: "OVERFLOW" redefined
  102 | #define OVERFLOW 3 /* overflow range error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:31: note: this is the location of the previous definition
   31 | #define OVERFLOW _OVERFLOW
      | 
In file included from hyp2f1.c:81:
./mconf.h:103: warning: "UNDERFLOW" redefined
  103 | #define UNDERFLOW 4 /* underflow range error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:32: note: this is the location of the previous definition
   32 | #define UNDERFLOW _UNDERFLOW
      | 
In file included from hyp2f1.c:81:
./mconf.h:104: warning: "TLOSS" redefined
  104 | #define TLOSS  5 /* total loss of precision */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:33: note: this is the location of the previous definition
   33 | #define TLOSS  _TLOSS
      | 
In file included from hyp2f1.c:81:
./mconf.h:105: warning: "PLOSS" redefined
  105 | #define PLOSS  6 /* partial loss of precision */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/Rmath.h:43,
                 from hyp2f1.c:80:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:34: note: this is the location of the previous definition
   34 | #define PLOSS  _PLOSS
      | 
gcc  -I"F:/biocbuild/bbs-3.15-bioc/R/include" -DNDEBUG     -I"C:/rtools42/x86_64-w64-mingw32.static.posix/include"  -D R_NO_REMAP -I.    -O2 -Wall  -std=gnu99 -mfpmath=sse -msse2 -mstackrealign  -c mtherr.c -o mtherr.o
In file included from mtherr.c:58:
./mconf.h:100: warning: "DOMAIN" redefined
  100 | #define DOMAIN  1 /* argument domain error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:29: note: this is the location of the previous definition
   29 | #define DOMAIN  _DOMAIN
      | 
In file included from mtherr.c:58:
./mconf.h:101: warning: "SING" redefined
  101 | #define SING  2 /* argument singularity */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:30: note: this is the location of the previous definition
   30 | #define SING  _SING
      | 
In file included from mtherr.c:58:
./mconf.h:102: warning: "OVERFLOW" redefined
  102 | #define OVERFLOW 3 /* overflow range error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:31: note: this is the location of the previous definition
   31 | #define OVERFLOW _OVERFLOW
      | 
In file included from mtherr.c:58:
./mconf.h:103: warning: "UNDERFLOW" redefined
  103 | #define UNDERFLOW 4 /* underflow range error */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:32: note: this is the location of the previous definition
   32 | #define UNDERFLOW _UNDERFLOW
      | 
In file included from mtherr.c:58:
./mconf.h:104: warning: "TLOSS" redefined
  104 | #define TLOSS  5 /* total loss of precision */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:33: note: this is the location of the previous definition
   33 | #define TLOSS  _TLOSS
      | 
In file included from mtherr.c:58:
./mconf.h:105: warning: "PLOSS" redefined
  105 | #define PLOSS  6 /* partial loss of precision */
      | 
In file included from F:/biocbuild/bbs-3.15-bioc/R/include/R.h:47,
                 from mtherr.c:56:
c:\rtools42\x86_64-w64-mingw32.static.posix\include\math.h:34: note: this is the location of the previous definition
   34 | #define PLOSS  _PLOSS
      | 
gcc -shared -s -static-libgcc -o Repitools.dll tmp.def const.o hyp2f1.o mtherr.o -LC:/rtools42/x86_64-w64-mingw32.static.posix/lib/x64 -LC:/rtools42/x86_64-w64-mingw32.static.posix/lib -LF:/biocbuild/bbs-3.15-bioc/R/bin/x64 -lR
installing to F:/biocbuild/bbs-3.15-bioc/R/library/00LOCK-Repitools/00new/Repitools/libs/x64
** R
** data
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (Repitools)

R version 4.2.1 (2022-06-23 ucrt) -- "Funny-Looking Kid"
Copyright (C) 2022 The R Foundation for Statistical Computing
Platform: x86_64-w64-mingw32/x64 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> require("Repitools")
Loading required package: Repitools
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which.max, which.min

> require("BSgenome.Hsapiens.UCSC.hg18")
Loading required package: BSgenome.Hsapiens.UCSC.hg18
Loading required package: BSgenome
Loading required package: S4Vectors
Loading required package: stats4

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    I, expand.grid, unname

Loading required package: IRanges

Attaching package: 'IRanges'

The following object is masked from 'package:grDevices':

    windows

Loading required package: GenomeInfoDb
Loading required package: GenomicRanges
Loading required package: Biostrings
Loading required package: XVector

Attaching package: 'Biostrings'

The following object is masked from 'package:base':

    strsplit

Loading required package: rtracklayer

Attaching package: 'rtracklayer'

The following object is masked from 'package:Repitools':

    blocks

> options(warn = -1)
> 
> probes <- data.frame(chr = c("chr1", "chr9", "chrY", "chr1", "chr21", "chr6", "chr6", "chr2", "chrX", "chr11"), position = c(10000, 5500, 100000, 11000, 20000000, 500100, 499900, 700000, 9900, 90000), strand = c('+', '+', '+', '+', '-', '-', '-', '+', '-', '+'), stringsAsFactors = FALSE)
> genes <- data.frame(chr = c("chr1", "chr9", "chr11", "chr1", "chr11", "chr6", "chr6", "chr22", "chrY", "chr21"), start = c(10000, 7900, 950000, 10500, 74000000, 450000, 5000000, 44000000, 1500, 9800000), end = c(12500, 9500, 1000000, 14500, 75000000, 500000, 9000000, 45000000, 3000, 10000000), strand = c('+', '-', '-', '+', '-', '-', '-', '+', '+', '-'), name = paste("Gene", 1:10), stringsAsFactors = FALSE)
> 
> crossMatch <- annotationLookup(probes, genes, 5000, 5000)
Processing mapping between probes and features.
Mapping done.
> correctCrossMatch <- list(indexes = list(`Gene 1` = as.integer(c(1, 4)), `Gene 2` = as.integer(2), `Gene 3` = integer(), `Gene 4` = as.integer(c(1, 4)), `Gene 5` = integer(), `Gene 6` = as.integer(c(6, 7)), `Gene 7` = integer(), `Gene 8` = integer(), `Gene 9` = integer(), `Gene 10` = integer()), offsets = list(`Gene 1` = as.integer(c(0, 1000)), `Gene 2` = as.integer(4000), `Gene 3` = numeric(), `Gene 4` = as.integer(c(-500, 500)), `Gene 5` = numeric(), `Gene 6` = as.integer(c(-100, 100)), `Gene 7` = numeric(), `Gene 8` = numeric(), `Gene 9` = numeric(), `Gene 10` = numeric()))
> names(correctCrossMatch$offsets$`Gene 1`) <- c(1, 4)
> names(correctCrossMatch$offsets$`Gene 2`) <- c(2)
> names(correctCrossMatch$offsets$`Gene 4`) <- c(1, 4)
> names(correctCrossMatch$offsets$`Gene 6`) <- c(6, 7)
> names(correctCrossMatch$offsets$`Gene 8`) <- character()
> names(correctCrossMatch$offsets$`Gene 9`) <- character()
> 
> if(!isTRUE(all.equal(crossMatch, correctCrossMatch))) 
+ 	stop("Error in annotationLookup function.")
> cat("anontationLookup tested fine.\n")
anontationLookup tested fine.
> 
> lookupTable <- makeWindowLookupTable(crossMatch$indexes, crossMatch$offsets, starts = seq(-5000, 4900, 100), ends = seq(-4900, 5000, 100))
> correctLookupTable <- matrix(NA, nrow = 10, ncol = 100, dimnames = list(genes$names, seq(-4950, 4950, 100)))
> correctLookupTable[1, c(50, 51)] <- 1
> correctLookupTable[1, c(60, 61)] <- 4
> correctLookupTable[2, c(90, 91)] <- 2
> correctLookupTable[4, c(45, 46)] <- 1
> correctLookupTable[4, c(55, 56)] <- 4
> correctLookupTable[6, c(49, 50)] <- 6
> correctLookupTable[6, c(51, 52)] <- 7
> 
> if(!all(lookupTable == correctLookupTable, na.rm = TRUE))
+     stop("Error in makeWindowLookupTable function")
> cat("makeWindowLookupTable tested fine.\n")
makeWindowLookupTable tested fine.
> 
> cpgDensity <- cpgDensityCalc(genes, organism = Hsapiens, window = 500, w.function="linear")
CpG density calculated for a sample.
> if(!isTRUE(all.equal(cpgDensity, c(5.784, 7.620, 5.828, 2.928, 2.080, 1.252, 0.000, 7.404, 3.928, 0.000))))
+     stop("cpgDensityCalc not working for window = 500, scaling = linear")
> cpgDensity <- cpgDensityCalc(genes, window = 100, w.function = "log", organism = Hsapiens)
CpG density calculated for a sample.
> if(!isTRUE(all.equal(round(cpgDensity, 3), c(2.424, 1.882, 1.436, 0.084, 0.379, 0.000, 0.000, 0.263, 1.392, 0.000))))
+     stop("cpgDensityCalc not working for window = 100, scaling = log")
> cpgDensity <- cpgDensityCalc(genes, window = 1000, w.function = "exp", organism = Hsapiens)
CpG density calculated for a sample.
> if(!isTRUE(all.equal(round(cpgDensity, 3), c(4.874, 5.835, 4.999, 2.239, 1.567, 0.851, 0.054, 5.589, 3.229,0.062))))
+     stop("cpgDensityCalc not working for window = 1000, scaling = exp")
> cpgDensity <- cpgDensityCalc(genes, window = 500, w.function = "none", organism = Hsapiens)
CpG density calculated for a sample.
> if(!isTRUE(all.equal(cpgDensity, c(11, 14, 16, 6, 4, 2, 0, 15, 9, 0))))
+     stop("cpgDensityCalc not working for window = 500, scaling = none")
> cat("cpgDensityCalc tested fine.\n")
cpgDensityCalc tested fine.
> 
> GCpercent <- gcContentCalc(genes, Hsapiens, 500)
Calculating GC content.
> if(!isTRUE(all.equal(GCpercent, c(0.504, 0.586, 0.560, 0.470, 0.540, 0.304, 0.356, 0.638, 0.444, 0.388))))
+     stop("Error in gcContentCalc function")
> cat("gcContentCalc tested fine.\n")
gcContentCalc tested fine.
> 
> findsCount <- sequenceCalc(genes, Hsapiens, 500, pattern = "AATT")
> if(!isTRUE(all.equal(findsCount, c(1, 1, 0, 2, 1, 8, 2, 0, 4, 10))))
+     stop("Error in sequenceCalc function counting task")
> 
> findsPlaces <- sequenceCalc(genes, Hsapiens, 500, pattern = "AATT", positions = TRUE)
> correctPlaces <- list(-62, 181, NULL, c(-140, -98), 231, c(-219, -146, -88, -12, 12, 182, 209, 214), c(-61, 60), NULL, c(-115, -30, 11, 80), c(-238, -228, -202, -189, -177, -106, -21, 148, 158, 238))
> if(!isTRUE(all.equal(findsPlaces, correctPlaces)))
+     stop("Error in sequenceCalc function positions task")
> cat("sequenceCalc tested fine.\n")
sequenceCalc tested fine.
> cat("All tests passed.\n")
All tests passed.
> 
> proc.time()
   user  system elapsed 
  81.43    3.57  307.45