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CHECK report for cobindR on malbec2

This page was generated on 2020-03-12 13:46:16 -0400 (Thu, 12 Mar 2020).

Package 334/1838HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
cobindR 1.25.0
Manuela Benary
Snapshot Date: 2020-03-11 16:45:12 -0400 (Wed, 11 Mar 2020)
URL: https://git.bioconductor.org/packages/cobindR
Branch: master
Last Commit: 4ab7bad
Last Changed Date: 2019-10-29 13:36:53 -0400 (Tue, 29 Oct 2019)
malbec2 Linux (Ubuntu 18.04.4 LTS) / x86_64  OK  OK [ ERROR ]
tokay2 Windows Server 2012 R2 Standard / x64  OK  OK  ERROR  OK 

Summary

Package: cobindR
Version: 1.25.0
Command: /home/biocbuild/bbs-3.11-bioc/R/bin/R CMD check --install=check:cobindR.install-out.txt --library=/home/biocbuild/bbs-3.11-bioc/R/library --no-vignettes --timings cobindR_1.25.0.tar.gz
StartedAt: 2020-03-12 02:28:06 -0400 (Thu, 12 Mar 2020)
EndedAt: 2020-03-12 02:34:12 -0400 (Thu, 12 Mar 2020)
EllapsedTime: 365.8 seconds
RetCode: 1
Status:  ERROR 
CheckDir: cobindR.Rcheck
Warnings: NA

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/bbs-3.11-bioc/R/bin/R CMD check --install=check:cobindR.install-out.txt --library=/home/biocbuild/bbs-3.11-bioc/R/library --no-vignettes --timings cobindR_1.25.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/home/biocbuild/bbs-3.11-bioc/meat/cobindR.Rcheck’
* using R Under development (unstable) (2020-01-28 r77731)
* using platform: x86_64-pc-linux-gnu (64-bit)
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘cobindR/DESCRIPTION’ ... OK
* this is package ‘cobindR’ version ‘1.25.0’
* checking package namespace information ... OK
* checking package dependencies ... NOTE
Package which this enhances but not available for checking: ‘genoPlotR’
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘cobindR’ can be installed ... WARNING
Found the following significant warnings:
  Warning: multiple methods tables found for ‘path’
  Warning: multiple methods tables found for ‘path<-’
See ‘/home/biocbuild/bbs-3.11-bioc/meat/cobindR.Rcheck/00install.out’ for details.
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... NOTE
Malformed Description field: should contain one or more complete sentences.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... NOTE
Warning: multiple methods tables found for ‘path’
Warning: multiple methods tables found for ‘path<-’

A namespace must be able to be loaded with just the base namespace
loaded: otherwise if the namespace gets loaded by a saved object, the
session will be unable to start.

Probably some imports need to be declared in the NAMESPACE file.
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
'library' or 'require' calls in package code:
  ‘MotifDb’ ‘parallel’ ‘snowfall’
  Please use :: or requireNamespace() instead.
  See section 'Suggested packages' in the 'Writing R Extensions' manual.
* checking S3 generic/method consistency ... NOTE
Found the following apparent S3 methods exported but not registered:
  plot.detrending plot.gc plot.pairdistance plot.positionprofile
  plot.positions plot.positions.simple plot.tfbs.heatmap
  plot.tfbs.venndiagram plot.tfbslogo
See section ‘Registering S3 methods’ in the ‘Writing R Extensions’
manual.
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
compare.samples: no visible global function definition for
  ‘wilcox.test’
input.pfm.similarity: no visible global function definition for ‘combn’
parallelize: no visible global function definition for
  ‘installed.packages’
parallelize: no visible global function definition for ‘mclapply’
parallelize: no visible global function definition for ‘sfCpus’
parallelize: no visible global function definition for ‘sfInit’
parallelize: no visible global function definition for ‘sfLapply’
parallelize: no visible global function definition for ‘sfStop’
query.motifDb: no visible binding for global variable ‘MotifDb’
find.pairs,cobindr: no visible global function definition for ‘combn’
plot.detrending,cobindr: no visible global function definition for
  ‘par’
plot.detrending,cobindr: no visible global function definition for
  ‘plot’
plot.detrending,cobindr: no visible global function definition for
  ‘lines’
plot.detrending,cobindr: no visible global function definition for
  ‘title’
plot.gc,cobindr: no visible global function definition for
  ‘txtProgressBar’
plot.gc,cobindr: no visible global function definition for
  ‘setTxtProgressBar’
plot.gc,cobindr: no visible global function definition for ‘rainbow’
plot.gc,cobindr: no visible global function definition for ‘par’
plot.gc,cobindr: no visible global function definition for ‘matplot’
plot.gc,cobindr: no visible global function definition for ‘points’
plot.gc,cobindr: no visible global function definition for ‘legend’
plot.pairdistance,cobindr: no visible global function definition for
  ‘hist’
plot.pairdistribution,cobindr: no visible global function definition
  for ‘plot’
plot.positionprofile,cobindr: no visible global function definition for
  ‘rainbow’
plot.positionprofile,cobindr: no visible global function definition for
  ‘matplot’
plot.positionprofile,cobindr: no visible global function definition for
  ‘legend’
plot.positions.simple,cobindr: no visible global function definition
  for ‘rainbow’
plot.positions.simple,cobindr: no visible global function definition
  for ‘par’
plot.positions.simple,cobindr: no visible global function definition
  for ‘plot’
plot.positions.simple,cobindr: no visible global function definition
  for ‘points’
plot.positions.simple,cobindr: no visible global function definition
  for ‘legend’
plot.positions,cobindr: no visible global function definition for
  ‘rainbow’
plot.positions,cobindr: no visible binding for global variable ‘n.cpu’
plot.positions,cobindr: no visible global function definition for
  ‘hclust’
plot.positions,cobindr: no visible global function definition for
  ‘dist’
plot.positions,cobindr: no visible global function definition for
  ‘order.dendrogram’
plot.positions,cobindr: no visible global function definition for
  ‘as.dendrogram’
plot.positions,cobindr: no visible global function definition for
  ‘grid.newpage’
plot.positions,cobindr: no visible global function definition for
  ‘pushViewport’
plot.positions,cobindr: no visible global function definition for
  ‘viewport’
plot.positions,cobindr: no visible global function definition for
  ‘plot_gene_map’
plot.positions,cobindr: no visible global function definition for
  ‘popViewport’
plot.positions,cobindr: no visible global function definition for
  ‘gpar’
plot.positions,cobindr: no visible global function definition for
  ‘grid_legend’
plot.tfbs.heatmap,cobindr: no visible global function definition for
  ‘phyper’
plot.tfbs.heatmap,cobindr: no visible global function definition for
  ‘heat.colors’
plot.tfbs.venndiagram,cobindr: no visible global function definition
  for ‘venn.diagram’
plot.tfbs.venndiagram,cobindr: no visible global function definition
  for ‘grid.draw’
plot.tfbslogo,cobindr : <anonymous>: no visible global function
  definition for ‘makePWM’
plot.tfbslogo,cobindr : <anonymous>: no visible global function
  definition for ‘seqLogo’
plot.tfbslogo,cobindr : <anonymous>: no visible global function
  definition for ‘grid.text’
plot.tfbslogo,cobindr : <anonymous>: no visible global function
  definition for ‘gpar’
read.pfm,configuration: no visible global function definition for
  ‘read.table’
read.sequences,configuration: no visible global function definition for
  ‘txtProgressBar’
read.sequences,configuration: no visible global function definition for
  ‘setTxtProgressBar’
read.sequences,configuration: no visible global function definition for
  ‘read.table’
search.gadem,cobindr : <anonymous>: no visible global function
  definition for ‘GADEM’
search.gadem,cobindr: no visible global function definition for ‘GADEM’
search.gadem,cobindr: no visible global function definition for
  ‘nMotifs’
search.pwm,cobindr: no visible global function definition for ‘error’
testCpG,cobindr: no visible global function definition for ‘hist’
testCpG,cobindr: no visible global function definition for ‘layout’
testCpG,cobindr: no visible global function definition for ‘par’
testCpG,cobindr: no visible global function definition for ‘barplot’
write.bindingsites.table,cobindr: no visible global function definition
  for ‘mcols’
write.bindingsites.table,cobindr: no visible global function definition
  for ‘write.table’
write.bindingsites,cobindr: no visible global function definition for
  ‘write.table’
write,cobindr-character: no visible global function definition for
  ‘write.table’
Undefined global functions or variables:
  GADEM MotifDb as.dendrogram barplot combn dist error gpar grid.draw
  grid.newpage grid.text grid_legend hclust heat.colors hist
  installed.packages layout legend lines makePWM matplot mclapply mcols
  n.cpu nMotifs order.dendrogram par phyper plot plot_gene_map points
  popViewport pushViewport rainbow read.table seqLogo setTxtProgressBar
  sfCpus sfInit sfLapply sfStop title txtProgressBar venn.diagram
  viewport wilcox.test write.table
Consider adding
  importFrom("grDevices", "heat.colors", "rainbow")
  importFrom("graphics", "barplot", "hist", "layout", "legend", "lines",
             "matplot", "par", "plot", "points", "title")
  importFrom("stats", "as.dendrogram", "dist", "hclust",
             "order.dendrogram", "phyper", "wilcox.test")
  importFrom("utils", "combn", "installed.packages", "read.table",
             "setTxtProgressBar", "txtProgressBar", "write.table")
to your NAMESPACE file.
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... ERROR
Running examples in ‘cobindR-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: search.pwm
> ### Title: function to predict transcription factor binding sites using the
> ###   method matchPWM from package Biostrings
> ### Aliases: search.pwm search.pwm-method search.pwm,cobindr-method
> ### Keywords: manip iteration methods
> 
> ### ** Examples
> 
> ############################################################
> # use simulated sequences
> library(Biostrings)
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: ‘BiocGenerics’

The following objects are masked from ‘package:parallel’:

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ,
    clusterExport, clusterMap, parApply, parCapply, parLapply,
    parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from ‘package:cobindR’:

    path, path<-

The following objects are masked from ‘package:stats’:

    IQR, mad, sd, var, xtabs

The following objects are masked from ‘package:base’:

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which, which.max, which.min

Loading required package: S4Vectors
Loading required package: stats4

Attaching package: ‘S4Vectors’

The following object is masked from ‘package:base’:

    expand.grid

Loading required package: IRanges
Loading required package: XVector

Attaching package: ‘Biostrings’

The following object is masked from ‘package:base’:

    strsplit

> 
> n <- 400 # number of input sequences
> l <- 500 # length of sequences
> n.hits <- 250 # number of 'true' binding sites
> bases <- c("A","C","G","T") # alphabet
> # generate random input sequences with two groups with differing GC content
> seqs <- sapply(1:(3*n/4), function(x) paste(sample(bases, l, replace=TRUE, 
+ 		prob=c(.3,.22,.2,.28)), collapse=""))
> seqs <- append(seqs, sapply(1:(n/4), function(x) paste(sample(bases, l, replace=TRUE, 
+ 		prob=c(.25,.25,.25,.25)), collapse="")))
> path <- system.file('extdata/pfms/myod.tfpfm',package='cobindR')
> motif <- read.transfac.pfm(path)[[1]] # get PFM of binding site 
[1] "ES_Sox2_1_c1058"
[1] "ES_Klf4_3_c1373"
> # add binding sites with distance specificity
> for(position in c(110, 150)) {
+ 	hits <- apply(apply(motif, 2, function(x) sample(x=bases, size=n.hits, prob=x, 
+ 			replace=TRUE)), 1, paste, collapse='')
+ 	pos.hits <- round(rnorm(n.hits, mean=position, sd=8))
+ 	names(pos.hits) <- sample(1:n, n.hits)
+ 	for(i in 1:n.hits) substr(seqs[as.integer(names(pos.hits)[i])], start=pos.hits[i], 
+ 							stop=pos.hits[i]+ncol(motif)) <- hits[i] 
+ }
> #save sample sequences in fasta file
> tmp.file <- tempfile(pattern = "cobindr_sample_seq", tmpdir = tempdir(), fileext = ".fasta")
> writeXStringSet(DNAStringSet(seqs), tmp.file)
> #run cobindr
> cfg <- cobindRConfiguration()
Warning in .local(.Object, ...) :
  no config-file defined, generating configuration-object with default values
> sequence_type(cfg) <- 'fasta'
> sequence_source(cfg) <- tmp.file
> sequence_origin(cfg) <- 'artificial sequences'
> pfm_path(cfg) <- system.file('extdata/pfms',package='cobindR')
> pairs(cfg) <- 'V$MYOD_01 V$MYOD_01' 
> runObj <- cobindr(cfg, name='cobindr test using sampled sequences')
[1] "Creating a new experiment!"
reading file /tmp/Rtmp8Cpw2r/cobindr_sample_seq1d2c68a56f7b.fasta ...

  |                                                                            
  |                                                                      |   0%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

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  |=                                                                     |   1%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
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  implicit list embedding of S4 objects is deprecated

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  |=                                                                     |   2%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

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  |==                                                                    |   2%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

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  |==                                                                    |   3%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  |==                                                                    |   4%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

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  |===                                                                   |   4%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

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  |===                                                                   |   5%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

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  |====                                                                  |   5%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====                                                                  |   6%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====                                                                 |   6%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====                                                                 |   7%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====                                                                 |   8%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======                                                                |   8%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======                                                                |   9%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======                                                               |  10%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========                                                              |  11%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========                                                              |  12%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
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  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========                                                             |  12%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========                                                             |  13%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

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  |=========                                                             |  14%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========                                                            |  14%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========                                                            |  15%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========                                                           |  15%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========                                                           |  16%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============                                                          |  16%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============                                                          |  17%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============                                                          |  18%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============                                                         |  18%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============                                                         |  19%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============                                                        |  20%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============                                                       |  21%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============                                                       |  22%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================                                                      |  22%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================                                                      |  23%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================                                                      |  24%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================                                                     |  24%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================                                                     |  25%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================                                                    |  25%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================                                                    |  26%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================                                                   |  26%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================                                                   |  27%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================                                                   |  28%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================                                                  |  28%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================                                                  |  29%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================                                                 |  30%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================                                                |  31%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================                                                |  32%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================                                               |  32%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================                                               |  33%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================                                               |  34%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================                                              |  34%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================                                              |  35%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================                                             |  35%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================                                             |  36%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================                                            |  36%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================                                            |  37%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================                                            |  38%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================                                           |  38%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================                                           |  39%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================                                          |  40%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================                                         |  41%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================                                         |  42%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================                                        |  42%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================                                        |  43%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================                                        |  44%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================                                       |  44%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================                                       |  45%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================                                      |  45%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================                                      |  46%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================                                     |  46%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================                                     |  47%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================                                     |  48%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================                                    |  48%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================                                    |  49%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================                                   |  50%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================                                  |  51%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================                                  |  52%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================================                                 |  52%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================================                                 |  53%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================================                                 |  54%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================                                |  54%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================                                |  55%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================================                               |  55%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================================                               |  56%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================================                              |  56%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================================                              |  57%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================================                              |  58%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================================                             |  58%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================================                             |  59%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================================                            |  60%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================================                           |  61%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================================                           |  62%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================================                          |  62%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================================                          |  63%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================================                          |  64%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================================                         |  64%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================================                         |  65%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================================                        |  65%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================================                        |  66%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================================                       |  66%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================================                       |  67%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================================                       |  68%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================================                      |  68%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================================                      |  69%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================================                     |  70%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================================                    |  71%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================================                    |  72%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================                   |  72%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================                   |  73%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================                   |  74%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================================                  |  74%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================================                  |  75%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================================================                 |  75%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=====================================================                 |  76%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================================                |  76%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================================                |  77%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================================                |  78%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================================================               |  78%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=======================================================               |  79%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |========================================================              |  80%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================================================             |  81%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=========================================================             |  82%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================================================            |  82%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================================================            |  83%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==========================================================            |  84%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================================================           |  84%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===========================================================           |  85%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================================================          |  85%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |============================================================          |  86%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================================================         |  86%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================================================         |  87%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=============================================================         |  88%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================================================        |  88%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==============================================================        |  89%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===============================================================       |  90%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================================================      |  91%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |================================================================      |  92%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================================================     |  92%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================================================     |  93%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |=================================================================     |  94%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================================================    |  94%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |==================================================================    |  95%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================================   |  95%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================================   |  96%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================================================  |  96%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================================================  |  97%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |====================================================================  |  98%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================================== |  98%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |===================================================================== |  99%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
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  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated

  |                                                                            
  |======================================================================| 100%Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
Warning in `[<-`(`*tmp*`, id, value = new.seq) :
  implicit list embedding of S4 objects is deprecated
ready retrieving sequences!
 reading pfm files: /home/biocbuild/bbs-3.11-bioc/R/library/cobindR/extdata/pfms ...
[1] "ES_Sox2_1_c1058"
[1] "ES_Klf4_3_c1373"
[1] "ES_Oct4_1_c570"
[1] "ES_Sox2_1_c1058"
ignored files:
 
Using the parallel (multicore) version of cobindR - function cpg.gc.content with 20 cores
> # perform tfbs prediction using matchPWM
> runObj.bs <- search.pwm(runObj, min.score = '90')
 ----------- FAILURE REPORT -------------- 
 --- failure: the condition has length > 1 ---
 --- srcref --- 
: 
 --- package (from environment) --- 
cobindR
 --- call from context --- 
FUN(X[[i]], ...)
 --- call from argument --- 
if (class(res) == "try-error") warning("PFM-PWM conversion failed for matrix ", 
    names(x@pfm)[x], "!")
 --- R stacktrace ---
where 1: FUN(X[[i]], ...)
where 2: lapply(1:length(x@pfm), function(y) {
    pwm = x@pfm[[y]]
    is.float = any(pwm != apply(pwm, c(1, 2), as.integer))
    if (is.float) {
        return(pwm)
    }
    else {
        res = try(pfm2pwm(pwm))
        if (class(res) == "try-error") 
            warning("PFM-PWM conversion failed for matrix ", 
                names(x@pfm)[x], "!")
        return(res)
    }
})
where 3: lapply(1:length(x@pfm), function(y) {
    pwm = x@pfm[[y]]
    is.float = any(pwm != apply(pwm, c(1, 2), as.integer))
    if (is.float) {
        return(pwm)
    }
    else {
        res = try(pfm2pwm(pwm))
        if (class(res) == "try-error") 
            warning("PFM-PWM conversion failed for matrix ", 
                names(x@pfm)[x], "!")
        return(res)
    }
})
where 4: .local(x, ...)
where 5: search.pwm(runObj, min.score = "90")
where 6: search.pwm(runObj, min.score = "90")

 --- value of length: 2 type: logical ---
[1] FALSE FALSE
 --- function from context --- 
function (y) 
{
    pwm = x@pfm[[y]]
    is.float = any(pwm != apply(pwm, c(1, 2), as.integer))
    if (is.float) {
        return(pwm)
    }
    else {
        res = try(pfm2pwm(pwm))
        if (class(res) == "try-error") 
            warning("PFM-PWM conversion failed for matrix ", 
                names(x@pfm)[x], "!")
        return(res)
    }
}
<environment: 0x55cc008eb328>
 --- function search by body ---
 ----------- END OF FAILURE REPORT -------------- 
Fatal error: the condition has length > 1
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘runTests.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 1 WARNING, 6 NOTEs
See
  ‘/home/biocbuild/bbs-3.11-bioc/meat/cobindR.Rcheck/00check.log’
for details.


Installation output

cobindR.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/bbs-3.11-bioc/R/bin/R CMD INSTALL cobindR
###
##############################################################################
##############################################################################


* installing to library ‘/home/biocbuild/bbs-3.11-bioc/R/library’
* installing *source* package ‘cobindR’ ...
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
Creating a new generic function for ‘sequence’ in package ‘cobindR’
Creating a new generic function for ‘path’ in package ‘cobindR’
Creating a new generic function for ‘path<-’ in package ‘cobindR’
Creating a generic function for ‘write’ from package ‘base’ in package ‘cobindR’
Creating a generic function for ‘write.fasta’ from package ‘seqinr’ in package ‘cobindR’
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
Warning: multiple methods tables found for ‘path’
Warning: multiple methods tables found for ‘path<-’
** testing if installed package can be loaded from final location
Warning: multiple methods tables found for ‘path’
Warning: multiple methods tables found for ‘path<-’
** testing if installed package keeps a record of temporary installation path
* DONE (cobindR)

Tests output

cobindR.Rcheck/tests/runTests.Rout


R Under development (unstable) (2020-01-28 r77731) -- "Unsuffered Consequences"
Copyright (C) 2020 The R Foundation for Statistical Computing
Platform: x86_64-pc-linux-gnu (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> BiocGenerics:::testPackage('cobindR', pattern="runit_.*\\.R$")

Attaching package: 'cobindR'

The following object is masked from 'package:base':

    sequence



RUNIT TEST PROTOCOL -- Thu Mar 12 02:34:07 2020 
*********************************************** 
Number of test functions: 0 
Number of errors: 0 
Number of failures: 0 

 
1 Test Suite : 
cobindR RUnit Tests - 0 test functions, 0 errors, 0 failures
Number of test functions: 0 
Number of errors: 0 
Number of failures: 0 
Warning messages:
1: multiple methods tables found for 'path' 
2: multiple methods tables found for 'path<-' 
> 
> proc.time()
   user  system elapsed 
 13.678   0.434  14.096 

Example timings

cobindR.Rcheck/cobindR-Ex.timings

nameusersystemelapsed
SeqObj-class0.0010.0010.001
bg_binding_sites6.7162.2395.613
bg_pairs4.6941.8464.080
bg_sequence_origin0.0050.0000.004
bg_sequence_source0.0040.0000.005
bg_sequence_type0.0040.0000.003
bg_sequences4.2991.7653.698
binding_sites3.9881.9063.430
cobindRConfiguration0.0020.0000.002
cobindr-class0.0010.0000.000
comment0.0910.0040.095
configuration-class0.0010.0000.001
configuration4.2532.0793.686
downstream0.0040.0000.004
experiment_description5.3642.4654.280
fdrThreshold0.0040.0000.004
get.bindingsite.ranges000
id0.0040.0000.004
location0.1630.0040.167
mart0.0040.0000.003
max_distance0.0030.0000.004
name0.1550.0000.155
pValue0.0040.0000.003
pairs0.0040.0000.004
pairs_of_interest4.7062.1424.246
path0.0040.0000.004
pfm4.2352.0513.580
pfm_path0.0030.0000.002
plot.gc12.74851.09531.061
pseudocount0.0010.0050.006
rtfbs19.830 6.241 8.814
search.gadem13.666 2.72210.820